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      The central role of symptom severity and associated characteristics for functional impairment in misophonia

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          Abstract

          Misophonia is characterized by a preoccupation with and strong emotional and behavioral reactions to certain triggers, mostly sounds related to eating and breathing. We applied functional impairment due to misophonic symptoms as a central criterion to investigate differences between clinical misophonia and normative decreased sound tolerance in a large non-random sample of n = 1,881 individuals from an online survey. We assessed the frequency of self-reported misophonia symptoms across various symptom measures, compared severity, triggers and emotional reactions, general psychopathology, interpersonal emotion regulation, and quality of life between both groups with and without functional impairing misophonia. Individuals with functional impairment due to misophonia ( n = 839) revealed significantly higher general psychopathology symptoms, lower interpersonal emotion regulation skills, and lower quality of life than individuals without impairment ( n = 1,042). Anxious/distressed and annoyed reactions to triggers were experienced more frequently compared to emotional reactions of disgust and sadness or depression in both groups. Overall, the group differences were primarily quantitative in nature. We discuss practical implications regarding classification and treatment and provide cutoffs for each symptom measure derived from group assignment for functional impairment.

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          Most cited references39

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          pROC: an open-source package for R and S+ to analyze and compare ROC curves

          Background Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often reached through inconsistent use or insufficient statistical analysis. To support researchers in their ROC curves analysis we developed pROC, a package for R and S+ that contains a set of tools displaying, analyzing, smoothing and comparing ROC curves in a user-friendly, object-oriented and flexible interface. Results With data previously imported into the R or S+ environment, the pROC package builds ROC curves and includes functions for computing confidence intervals, statistical tests for comparing total or partial area under the curve or the operating points of different classifiers, and methods for smoothing ROC curves. Intermediary and final results are visualised in user-friendly interfaces. A case study based on published clinical and biomarker data shows how to perform a typical ROC analysis with pROC. Conclusions pROC is a package for R and S+ specifically dedicated to ROC analysis. It proposes multiple statistical tests to compare ROC curves, and in particular partial areas under the curve, allowing proper ROC interpretation. pROC is available in two versions: in the R programming language or with a graphical user interface in the S+ statistical software. It is accessible at http://expasy.org/tools/pROC/ under the GNU General Public License. It is also distributed through the CRAN and CSAN public repositories, facilitating its installation.
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            Answering the Call for a Standard Reliability Measure for Coding Data

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              The Work and Social Adjustment Scale: a simple measure of impairment in functioning

              Patients' perspectives concerning impaired functioning provide important information. To evaluate the reliability and validity of the Work and Social Adjustment Scale (WSAS). Data from two studies were analysed. Reliability analyses included internal scale consistency, test – retest and parallel forms. Convergent and criterion validities were examined with respect to disorder severity. Cronbach's α measure of internal scale consistency ranged from 0.70 to 0.94. Test – retest correlation was 0.73. Interactive voice response administrations of the WSAS gave correlations of 0.81 and 0.86 with clinician interviews. Correlations of WSAS with severity of depression and obsessive–compulsive disorder symptoms were 0.76 and 0.61, respectively. The scores were sensitive to patient differences in disorder severity and treatment-related change. The WSAS is a simple, reliable and valid measure of impaired functioning. It is a sensitive and useful outcome measure offering the potential for readily interpretable comparisons across studies and disorders.
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                Author and article information

                Contributors
                Journal
                Front Psychiatry
                Front Psychiatry
                Front. Psychiatry
                Frontiers in Psychiatry
                Frontiers Media S.A.
                1664-0640
                28 March 2023
                2023
                : 14
                : 1112472
                Affiliations
                Department of Psychology, Faculty of Psychology and Sports Science, Bielefeld University , Bielefeld, Germany
                Author notes

                Edited by: M. Zachary Rosenthal, Duke University, United States

                Reviewed by: Zachary J. Williams, Vanderbilt University, United States; Jamie Ward, University of Sussex, United Kingdom; Jane Gregory, University of Oxford, United Kingdom

                *Correspondence: Anne Möllmann, anne.moellmann@ 123456uni-bielefeld.de

                This article was submitted to Anxiety and Stress Disorders, a section of the journal Frontiers in Psychiatry

                Article
                10.3389/fpsyt.2023.1112472
                10086372
                37056403
                3fd98fe9-5749-445e-8e51-a3e9eca19439
                Copyright © 2023 Möllmann, Heinrichs, Illies, Potthast and Kley.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 30 November 2022
                : 08 March 2023
                Page count
                Figures: 1, Tables: 5, Equations: 0, References: 51, Pages: 13, Words: 9716
                Categories
                Psychiatry
                Original Research

                Clinical Psychology & Psychiatry
                misophonia,functional impairment,emotion regulation,decreased sound tolerance,misophonic reactions

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