Broader autism phenotype: evidence from a family history study of multiple-incidence autism families.

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Abstract

Studies of families ascertained through a single autistic proband suggest that the genetic liability for autism may be expressed in nonautistic relatives in a phenotype that is milder but qualitatively similar to the defining features of autism. The objective of this study was to examine behaviors that may define this broader phenotype in relatives ascertained through two autistic siblings.

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Journal

Journal ID (iso-abbrev): Am J Psychiatry

Title: The American journal of psychiatry

Publisher: American Psychiatric Association Publishing

ISSN: 0002-953X

ISSN (Print): 0002-953X

Publication date (Electronic): Feb 1997

Volume: 154

Issue: 2

Affiliations

[1 ] Department of Psychiatry, University of Iowa College of Medicine, Iowa City, USA. jpiven@blue.weeg.uiowa.edu

Article

DOI: 10.1176/ajp.154.2.185

PubMed ID: 9016266

SO-VID: 336d3970-8b6e-4f77-97da-021fca0b8333

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