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      Chronic Pain in the Emergency Department: A Pilot Mixed-Methods Cross-Sectional Study Examining Patient Characteristics and Reasons for Presentations

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          Abstract

          Background. Chronic pain (CP) accounts for 10–16% of emergency department (ED) visits, contributing to ED overcrowding and leading to adverse events. Objectives. To describe patients with CP attending the ED and identify factors contributing to their visit. Methods. We used a mixed-method design combining interviews and questionnaires addressing pain, psychological distress, signs of opioid misuse, and disability. Participants were adults who attended the EDs of a large academic tertiary care center for their CP problem. Results. Fifty-eight patients (66% women; mean age 46.5, SD = 16.9) completed the study. The most frequently cited reason (60%) for ED visits was inability to cope with pain. Mental health problems were common, including depression (61%) and anxiety (45%). Participants had questions about the etiology of their pain, concerns about severe pain-related impairment, and problems with medication renewals or efficacy and sometimes felt invalidated in the ED. Although most participants had a primary care physician, the ED was seen as the only or best option when pain became unmanageable. Conclusions. Patients with CP visiting the ED often present with complex difficulties that cannot be addressed in the ED. Better access to interdisciplinary pain treatment is needed to reduce the burden of CP on the ED.

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          Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians? diagnoses

          The aim of this study was to compare the validity of the Hospital Anxiety and Depression Scale (HADS), the WHO (five) Well Being Index (WBI-5), the Patient Health Questionnaire (PHQ), and physicians' recognition of depressive disorders, and to recommend specific cut-off points for clinical decision making. A total of 501 outpatients completed each of the three depression screening questionnaires and received the Structured Clinical Interview for DSM-IV (SCID) as the criterion standard. In addition, treating physicians were asked to give their psychiatric diagnoses. Criterion validity and Receiver Operating Characteristics (ROC) were determined. Areas under the curves (AUCs) were compared statistically. All depression scales showed excellent internal consistencies (Cronbach's alpha: 0.85-0.90). For 'major depressive disorder', the operating characteristics of the PHQ were significantly superior to both the HADS and the WBI-5. For 'any depressive disorder', the PHQ showed again the best operating characteristics but the overall difference did not reach statistical significance at the 5% level. Cut-off points that can be recommended for the screening of 'major depressive disorder' had sensitivities of 98% (PHQ), 94% (WBI-5), and 85% (HADS). Corresponding specificities were 80% (PHQ), 78% (WBI-5), and 76% (HADS). In contrast, physicians' recognition of 'major depressive disorder' was poor (sensitivity, 40%; specificity, 87%). Our sample may not be representative of medical outpatients, but sensitivity and specificity are independent of disorder prevalence. All three questionnaires performed well in depression screening, but significant differences in criterion validity existed. These results may be helpful in the selection of questionnaires and cut-off points.
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            Achieving Saturation in Thematic Analysis: Development and Refinement of a Codebook

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              Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone.

              Opioid-related mortality appears to be increasing in Canada. We examined the true extent of the problem and the impact of the introduction of long-acting oxycodone. We examined trends in the prescribing of opioid analgesics in the province of Ontario from 1991 to 2007. We reviewed all deaths related to opioid use between 1991 and 2004. We linked 3271 of these deaths to administrative data to examine the patients' use of health care services before death. Using time-series analysis, we determined whether the addition of long-acting oxycodone to the provincial drug formulary in January 2000 was associated with an increase in opioid-related mortality. From 1991 to 2007, annual prescriptions for opioids increased from 458 to 591 per 1000 individuals. Opioid-related deaths doubled, from 13.7 per million in 1991 to 27.2 per million in 2004. Prescriptions of oxycodone increased by 850% between 1991 and 2007. The addition of long-acting oxycodone to the drug formulary was associated with a 5-fold increase in oxycodone-related mortality (p<0.01) and a 41% increase in overall opioid-related mortality (p=0.02). The manner of death was deemed unintentional by the coroner in 54.2% and undetermined in 21.9% of cases. Use of health care services in the month before death was common: for example, of the 3066 patients for whom data on physician visits were available, 66.4% had visited a physician in the month before death; of the 1095 patients for whom individual-level prescribing data were available, 56.1% had filled a prescription for an opioid in the month before death. Opioid-related deaths in Ontario have increased markedly since 1991. A significant portion of the increase was associated with the addition of long-acting oxycodone to the provincial drug formulary. Most of the deaths were deemed unintentional. The frequency of visits to a physician and prescriptions for opioids in the month before death suggests a missed opportunity for prevention.
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                Author and article information

                Journal
                Pain Res Manag
                Pain Res Manag
                PRM
                Pain Research & Management
                Hindawi Publishing Corporation
                1203-6765
                1918-1523
                2016
                18 October 2016
                : 2016
                : 3092391
                Affiliations
                1The Ottawa Hospital Research Institute, Ottawa, ON, Canada
                2Department of Anesthesiology, University of Ottawa, Ottawa, ON, Canada
                3The Ottawa Hospital Department of Psychology, Ottawa, ON, Canada
                4Faculty of Medicine, Memorial University, St. John's, NL, Canada
                5Department of Emergency Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
                6Children's Hospital of Eastern Ontario, Ottawa, ON, Canada
                7Carleton University, Ottawa, ON, Canada
                8York University, Toronto, ON, Canada
                9School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, ON, Canada
                Author notes
                *Patricia A. Poulin: ppoulin@ 123456toh.on.ca

                Academic Editor: Celeste C. Johnston

                Author information
                http://orcid.org/0000-0002-3934-9870
                http://orcid.org/0000-0001-8738-9503
                http://orcid.org/0000-0002-9435-1033
                http://orcid.org/0000-0002-7485-408X
                http://orcid.org/0000-0001-9075-9368
                http://orcid.org/0000-0002-4366-6713
                http://orcid.org/0000-0002-3978-8961
                Article
                10.1155/2016/3092391
                5088325
                27829785
                2b6f2693-eb08-46db-b806-afca328f4225
                Copyright © 2016 Patricia A. Poulin et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 21 October 2015
                : 10 August 2016
                : 6 September 2016
                Categories
                Research Article

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