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      Development and Validation of a Musculoskeletal Model of the Fully Articulated Thoracolumbar Spine and Rib Cage

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          Abstract

          We developed and validated a fully articulated model of the thoracolumbar spine in opensim that includes the individual vertebrae, ribs, and sternum. To ensure trunk muscles in the model accurately represent muscles in vivo, we used a novel approach to adjust muscle cross-sectional area (CSA) and position using computed tomography (CT) scans of the trunk sampled from a community-based cohort. Model predictions of vertebral compressive loading and trunk muscle tension were highly correlated to previous in vivo measures of intradiscal pressure (IDP), vertebral loading from telemeterized implants and trunk muscle myoelectric activity recorded by electromyography (EMG).

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          Author and article information

          Contributors
          Journal
          J Biomech Eng
          J Biomech Eng
          BIO
          Journal of Biomechanical Engineering
          American Society of Mechanical Engineers
          0148-0731
          1528-8951
          August 2015
          09 June 2015
          : 137
          : 8
          : 0810031-08100310
          Affiliations
          Harvard-MIT Health Sciences and

          Technology Program,

          Massachusetts Institute of Technology,

          Cambridge, MA 02139
          Center for Advanced Orthopaedic Studies,

          Beth Israel Deaconess Medical Center,

          330 Brookline Ave., RN121,

          Boston, MA 02215

          e-mail:  agbruno@ 123456mit.edu
          Harvard-MIT Health Sciences and

          Technology Program,

          Massachusetts Institute of Technology,

          Cambridge, MA 02139
          Center for Advanced Orthopaedic Studies,

          Beth Israel Deaconess Medical Center,

          330 Brookline Ave.,

          Boston, MA 02215
          Department of Orthopedic Surgery,

          Harvard Medical School,

          Boston, MA 02115

          e-mail:  mbouxsei@ 123456bidmc.harvard.edu
          Mem. ASME

          Center for Advanced Orthopaedic Studies,

          Beth Israel Deaconess Medical Center,

          330 Brookline Ave.,

          Boston, MA 02215
          Department of Orthopedic Surgery,

          Harvard Medical School,

          Boston, MA 02115

          e-mail:  danders7@ 123456bidmc.harvard.edu
          Author notes
          [1 ]Corresponding author.

          Manuscript received October 23, 2014; final manuscript received April 6, 2015; published online June 9, 2015. Assoc. Editor: Joel D. Stitzel.

          Article
          PMC5101035 PMC5101035 5101035 BIO-14-1531
          10.1115/1.4030408
          5101035
          25901907
          2b41fbac-4fae-40c2-bd23-0a796ba239b7
          Copyright © 2015 by ASME

          0148-0731/2015/137(08)/081003/10/ $25.00

          History
          : 23 October 2014
          : 06 April 2015
          Page count
          Pages: 10
          Categories
          Research Papers
          derivedfromresources, page
          Research Papers, derivedfromresources, page

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