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      SPARC Metrics Provide Mobility Smoothness Assessment in Oldest-Old With and Without a History of Falls: A Case Control Study

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          Abstract

          Aging-related neuromuscular and neurocognitive decline induces unsmooth movements in daily functional mobility. Here, we used a robust analysis of linear and angular spectral arc length (SPARC) in the single and dual task instrumented timed up-and-go (iTUG) test to compare functional mobility smoothness in fallers and non-fallers aged 85 and older. 64 participants aged 85 and older took part in this case control study. The case group (fallers, n = 32) had experienced falls to the ground in the 6 months prior to the assessment. SPARC analyses were conducted in all phases of the single and dual task iTUGs. We also performed correlation mapping to test the relation of socio-demographic and clinical features on SPARC metrics. The magnitude of between-group differences was calculated using D-Cohen effect size (ES). SPARC was able to distinguish fallers during the single iTUG (ES ≈ 4.18). Turning while walking in the iTUG induced pronounced unsmooth movements in the fallers (SPARC ≈ −13; ES = 3.52) and was associated with the ability to maintain balance in the functional reach task. This information is of importance in the study of functional mobility in the oldest-old and to assess the efficacy of fall-prevention programs.

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          Development and validation of a geriatric depression screening scale: a preliminary report.

          A new Geriatric Depression Scale (GDS) designed specifically for rating depression in the elderly was tested for reliability and validity and compared with the Hamilton Rating Scale for Depression (HRS-D) and the Zung Self-Rating Depression Scale (SDS). In constructing the GDS a 100-item questionnaire was administered to normal and severely depressed subjects. The 30 questions most highly correlated with the total scores were then selected and readministered to new groups of elderly subjects. These subjects were classified as normal, mildly depressed or severely depressed on the basis of Research Diagnostic Criteria (RDC) for depression. The GDS, HRS-D and SDS were all found to be internally consistent measures, and each of the scales was correlated with the subject's number of RDC symptoms. However, the GDS and the HRS-D were significantly better correlated with RDC symptoms than was the SDS. The authors suggest that the GDS represents a reliable and valid self-rating depression screening scale for elderly populations.
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            Normal cognitive aging.

            Even those who do not experience dementia or mild cognitive impairment may experience subtle cognitive changes associated with aging. Normal cognitive changes can affect an older adult's everyday function and quality of life, and a better understanding of this process may help clinicians distinguish normal from disease states. This article describes the neurocognitive changes observed in normal aging, followed by a description of the structural and functional alterations seen in aging brains. Practical implications of normal cognitive aging are then discussed, followed by a discussion of what is known about factors that may mitigate age-associated cognitive decline.
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              Development and initial validation of the Falls Efficacy Scale-International (FES-I).

              There is a need for a measure of fear of falling that assesses both easy and difficult physical activities and social activities and is suitable for use in a range of languages and cultural contexts, permitting direct comparison between studies and populations in different countries and settings. To develop a modified version of the Falls Efficacy Scale to satisfy this need, and to establish its psychometric properties, reliability, and concurrent validity (i.e. that it demonstrates the expected relationship with age, falls history and falls risk factors). Cross-sectional survey. Community sample. 704 people aged between 60 and 95 years completed The Falls Efficacy Scale-International (FES-I) either in postal self-completion format or by structured interview. The FES-I had excellent internal and test-retest reliability (Cronbach's alpha=0.96, ICC=0.96). Factor analysis suggested a unitary underlying factor, with two dimensions assessing concern about less demanding physical activities mainly in the home, and concern about more demanding physical activities mainly outside the home. The FES-I had slightly better power than the original FES items to discriminate differences in concern about falling between groups differentiated by sex, age, occupation, falls in the past year, and falls risk factors (chronic illness, taking multiple or psychoactive medications, dizziness). The FES-I has close continuity with the best existing measure of fear of falling, excellent psychometric properties, and assesses concerns relating to basic and more demanding activities, both physical and social. Further research is required to confirm cross-cultural and predictive validity.
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                Author and article information

                Contributors
                Journal
                Front Physiol
                Front Physiol
                Front. Physiol.
                Frontiers in Physiology
                Frontiers Media S.A.
                1664-042X
                10 June 2020
                2020
                : 11
                : 540
                Affiliations
                [1] 1Biomedical Gerontology Program, School of Medicine, Pontifical Catholic University of Rio Grande do Sul , Porto Alegre, Brazil
                [2] 2Neuroplasticity and Rehabilitation Research Group (NEUROPLAR), Pontifical Catholic University of Rio Grande do Sul , Porto Alegre, Brazil
                [3] 3KITE – Toronto Rehabilitation Institute, University Health Network , Toronto, ON, Canada
                [4] 4School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul , Porto Alegre, Brazil
                [5] 5Department of Physical Therapy, Federal University of Health Sciences of Porto Alegre , Porto Alegre, Brazil
                [6] 6School of Health Sciences, University of Salford Manchester , Salford, United Kingdom
                Author notes

                Edited by: Ronald F. Zernicke, University of Michigan, United States

                Reviewed by: Peter C. Fino, The University of Utah, United States; Kohei Watanabe, Chukyo University, Japan

                *Correspondence: Régis Gemerasca Mestriner, regis.mestriner@ 123456pucrs.br

                These authors have contributed equally to this work

                ORCID: Anelise Ineu Figueiredo, orcid.org/0000-0002-7133-0432; Gustavo Balbinot, orcid.org/0000-0003-2870-3966; Fabiane Oliveira Brauner, orcid.org/0000-0001-5763-7537; Aniuska Schiavo, orcid.org/0000-0002-3356-0149; Rafael Reimann Baptista, orcid.org/0000-0003-1937-6393; Aline Souza Pagnussat, orcid.org/0000-0001-7837-5855; Kristen Hollands, orcid.org/0000-0002-3691-9532; Régis Gemerasca Mestriner, orcid.org/0000-0001-9837-1691

                This article was submitted to Integrative Physiology, a section of the journal Frontiers in Physiology

                Article
                10.3389/fphys.2020.00540
                7298141
                32587523
                269e5660-96d9-4902-84c3-cb418d1a64ff
                Copyright © 2020 Figueiredo, Balbinot, Brauner, Schiavo, Baptista, Pagnussat, Hollands and Mestriner.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 30 December 2019
                : 30 April 2020
                Page count
                Figures: 3, Tables: 3, Equations: 1, References: 46, Pages: 11, Words: 0
                Categories
                Physiology
                Original Research

                Anatomy & Physiology
                movement smoothness,functional mobility,falls,aging,oldest-old
                Anatomy & Physiology
                movement smoothness, functional mobility, falls, aging, oldest-old

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