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      Factors Associated With Psychological Outcomes Among Vaccinated and Unvaccinated Health Care Workers Against COVID-19 Infection in Bangladesh

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          Abstract

          Background

          Vaccination of healthcare workers (HCWs) is recommended during the COVID-19 pandemic to reduce the risk of infection for themselves and their patients, as well as to encourage their patients to get immunized. The present study aimed to investigate the psychological outcomes and associated factors among vaccinated and unvaccinated HCWs against COVID-19 infection in Bangladesh.

          Methods

          From March to August 2021, an online nationwide survey was conducted with a total of 2,038 Bangladeshi HCWs. The frequency of symptoms of general health problems, depression, anxiety, stress, post-traumatic stress disorder, insomnia, and loneliness was assessed using the Bangla versions of the GHQ-12, PHQ-2, GAD-2, PSS-4, PC-PTSD-5, ISI, and UCLA-LS scales, respectively.

          Results

          Compared with unvaccinated HCWs ( n = 1,058), vaccinated HCWs ( n = 980) had a statistically significant lower prevalence of general health problems (16.7 vs. 59.1%), depression (15.6 vs. 31.9%), post-traumatic stress disorder (22.3 vs. 30.8%), insomnia (23.8 vs. 64.9%), and loneliness symptoms (13.9 vs. 21.8%). Among vaccinated HCWs, females were significantly associated with a higher risk of symptoms of general health problems (AOR, 2.71; 95% CI, 0.97–7.60), anxiety (AOR, 2.17; 95% CI, 1.14–4.13), and loneliness (AOR, 2.52; 95% CI, 1.11–5.73). Except for anxiety and post-traumatic stress disorder symptoms, participants living in urban areas had a significantly lower risk of all psychological outcomes (e.g., depression: AOR, 0.43; 95% CI, 0.27–0.67; stress: AOR, 0.64; 95% CI, 0.47–0.88). Respondents who were married were significantly less likely to experience symptoms of general health problems (AOR, 0.10; 95% CI, 0.02–0.39), depression (AOR, 0.31; 95% CI, 0.22–0.82), insomnia (AOR, 0.46; 95% CI, 0.20–1.03), and loneliness (AOR, 0.31; 95% CI, 0.10-0.92). Participants who worked as doctors were significantly less chance of experiencing symptoms of general health problems (AOR, 0.18; 95% CI, 0.08–0.37), depression (AOR, 0.51; 95% CI, 0.30–0.87), and anxiety (AOR, 0.54; 95% CI, 0.37–0.78). On the other hand, unvaccinated HCWs who were 18–29 years old and had <5 years of work experience were significantly associated with a higher risk of all psychological outcomes except anxiety and insomnia symptoms (e.g., depression among 18–29 years old: AOR, 1.83; 95% CI, 0.27–2.60; stress among those with <5 years of work experience: AOR, 2.37; 95% CI, 0.93–6.07). Participants who worked as nurses were significantly more likely to suffer from depression (AOR, 1.44; 95% CI, 0.84–2.46), anxiety (AOR, 1.42; 95% CI, 0.24–1.73), and stress (AOR, 1.55; 95% CI, 0.31–0.89) symptoms. Except for anxiety and stress symptoms, respondents who worked as frontline workers and provided direct care to infected patients were the significantly higher chance of experiencing all psychological outcomes (e.g., depression among who worked as frontline workers: AOR, 2.41; 95% CI, 0.23–3.73; insomnia among those who provide direct care to infected patients: AOR, 2.60; 95% CI, 0.34–3.06). Participants who were infected with COVID-19 had a significantly less chance of experiencing symptoms of general health problems (AOR, 0.89; 95% CI, 0.65–1.22), depression (AOR, 0.66; 95% CI, 0.48–0.92), and anxiety (AOR, 0.63; 95% CI, 0.46–0.87).

          Conclusions

          To control the infection and improve psychological outcomes, this study suggests emphasizing the vaccinated to unvaccinated HCWs as soon as possible. They also required special attention, health-related education, and psychological support.

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          Most cited references77

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          A Global Measure of Perceived Stress

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            Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019

            Key Points Question What factors are associated with mental health outcomes among health care workers in China who are treating patients with coronavirus disease 2019 (COVID-19)? Findings In this cross-sectional study of 1257 health care workers in 34 hospitals equipped with fever clinics or wards for patients with COVID-19 in multiple regions of China, a considerable proportion of health care workers reported experiencing symptoms of depression, anxiety, insomnia, and distress, especially women, nurses, those in Wuhan, and front-line health care workers directly engaged in diagnosing, treating, or providing nursing care to patients with suspected or confirmed COVID-19. Meaning These findings suggest that, among Chinese health care workers exposed to COVID-19, women, nurses, those in Wuhan, and front-line health care workers have a high risk of developing unfavorable mental health outcomes and may need psychological support or interventions.
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              Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures

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                Author and article information

                Contributors
                Journal
                Front Med (Lausanne)
                Front Med (Lausanne)
                Front. Med.
                Frontiers in Medicine
                Frontiers Media S.A.
                2296-858X
                24 March 2022
                2022
                24 March 2022
                : 9
                : 852922
                Affiliations
                [1] 1Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, China
                [2] 2The Key Laboratory of Mental Disorder Management in Zhejiang Province , Hangzhou, China
                [3] 3Department of Periodontology and Oral Pathology, Holy Family Red Crescent Medical College and Hospital , Dhaka, Bangladesh
                [4] 4Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya , Kuala Lumpur, Malaysia
                [5] 5Department of Psychiatry, Fuyang Third Peoples Hospital , Hangzhou, China
                Author notes

                Edited by: Aida Bianco, University Magna Graecia of Catanzaro, Italy

                Reviewed by: Xiuli Song, Yantai Affiliated Hospital of Binzhou Medical University, China; Rocco Servidio, University of Calabria, Italy

                *Correspondence: Yi Xu xuyizju@ 123456zju.edu.cn

                This article was submitted to Infectious Diseases – Surveillance, Prevention and Treatment, a section of the journal Frontiers in Medicine

                Article
                10.3389/fmed.2022.852922
                8988188
                35402432
                23254181-4423-4722-97aa-ac29fe3152f5
                Copyright © 2022 Alam, Paul, Momi, Ni and Xu.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 11 January 2022
                : 14 February 2022
                Page count
                Figures: 0, Tables: 4, Equations: 0, References: 85, Pages: 13, Words: 10306
                Funding
                Funded by: National Natural Science Foundation of China, doi 10.13039/501100001809;
                Award ID: 81801340
                Funded by: Natural Science Foundation of Zhejiang Province, doi 10.13039/501100004731;
                Categories
                Medicine
                Original Research

                bangladesh,covid-19,health care workers,immunization,psychological outcomes,refusal,uptake

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