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      Prevalence and predictive value of ICD‐11 post‐traumatic stress disorder and Complex PTSD diagnoses in children and adolescents exposed to a single‐event trauma

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          Abstract

          Background

          The 11th edition of the International Classification of Diseases (ICD‐11) made a number of significant changes to the diagnostic criteria for post‐traumatic stress disorder (PTSD). We sought to determine the prevalence and 3‐month predictive values of the new ICD‐11 PTSD criteria relative to ICD‐10 PTSD, in children and adolescents following a single traumatic event. ICD‐11 also introduced a diagnosis of Complex PTSD (CPTSD), proposed to typically result from prolonged, chronic exposure to traumatic experiences, although the CPTSD diagnostic criteria do not require a repeated experience of trauma. We therefore explored whether children and adolescents demonstrate ICD‐11 CPTSD features following exposure to a single‐incident trauma.

          Method

          Data were analysed from a prospective cohort study of youth aged 8–17 years who had attended an emergency department following a single trauma. Assessments of PTSD, CPTSD, depressive and anxiety symptoms were performed at two to four weeks ( n = 226) and nine weeks ( n = 208) post‐trauma, allowing us to calculate and compare the prevalence and predictive value of ICD‐10 and ICD‐11 PTSD criteria, along with CPTSD. Predictive abilities of different diagnostic thresholds were undertaken using positive/negative predictive values, sensitivity/specificity statistics and logistic regressions.

          Results

          At Week 9, 15 participants (7%) were identified as experiencing ICD‐11 PTSD, compared to 23 (11%) experiencing ICD‐10 PTSD. There was no significant difference in comorbidity rates between ICD‐10 and ICD‐11 PTSD diagnoses. Ninety per cent of participants with ICD‐11 PTSD also met criteria for at least one CPTSD feature. Five participants met full CPTSD criteria.

          Conclusions

          Reduced prevalence of PTSD associated with the use of ICD‐11 criteria is likely to reduce identification of PTSD relative to using ICD‐10 criteria but not relative to DSM‐4 and DSM‐5 criteria. Diagnosis of CPTSD is likely to be infrequent following single‐incident trauma.

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          Most cited references23

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          The International Trauma Questionnaire: development of a self-report measure of ICD-11 PTSD and complex PTSD.

          The purpose of this study was to finalize the development of the International Trauma Questionnaire (ITQ), a self-report diagnostic measure of post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD), as defined in the 11th version of the International Classification of Diseases (ICD-11).
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            Disorders of extreme stress: The empirical foundation of a complex adaptation to trauma.

            Children and adults exposed to chronic interpersonal trauma consistently demonstrate psychological disturbances that are not captured in the posttraumatic stress disorder (PTSD) diagnosis. The DSM-IV (American Psychiatric Association, 1994) Field Trial studied 400 treatment-seeking traumatized individuals and 128 community residents and found that victims of prolonged interpersonal trauma, particularly trauma early in the life cycle, had a high incidence of problems with (a) regulation of affect and impulses, (b) memory and attention, (c) self-perception, (d) interpersonal relations, (e) somatization, and (f) systems of meaning. This raises important issues about the categorical versus the dimensional nature of posttraumatic stress, as well as the issue of comorbidity in PTSD. These data invite further exploration of what constitutes effective treatment of the full spectrum of posttraumatic psychopathology.
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              A review of current evidence regarding the ICD-11 proposals for diagnosing PTSD and complex PTSD.

              The World Health Organization's proposals for posttraumatic stress disorder (PTSD) in the 11th edition of the International Classification of Diseases, scheduled for release in 2018, involve a very brief set of symptoms and a distinction between two sibling disorders, PTSD and Complex PTSD. This review of studies conducted to test the validity and implications of the diagnostic proposals generally supports the proposed 3-factor structure of PTSD symptoms, the 6-factor structure of Complex PTSD symptoms, and the distinction between PTSD and Complex PTSD. Estimates derived from DSM-based items suggest the likely prevalence of ICD-11 PTSD in adults is lower than ICD-10 PTSD and lower than DSM-IV or DSM-5 PTSD, but this may change with the development of items that directly measure the ICD-11 re-experiencing requirement. Preliminary evidence suggests the prevalence of ICD-11 PTSD in community samples of children and adolescents is similar to DSM-IV and DSM-5. ICD-11 PTSD detects some individuals with significant impairment who would not receive a diagnosis under DSM-IV or DSM-5. ICD-11 CPTSD identifies a distinct group who have more often experienced multiple and sustained traumas and have greater functional impairment than those with PTSD.
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                Author and article information

                Contributors
                Caitlin.Hitchcock@mrc-cbu.cam.ac.uk
                Journal
                J Child Psychol Psychiatry
                J Child Psychol Psychiatry
                10.1111/(ISSN)1469-7610
                JCPP
                Journal of Child Psychology and Psychiatry, and Allied Disciplines
                John Wiley and Sons Inc. (Hoboken )
                0021-9630
                1469-7610
                28 April 2020
                March 2021
                : 62
                : 3 ( doiID: 10.1111/jcpp.v62.3 )
                : 270-276
                Affiliations
                [ 1 ] MRC: Cognition and Brain Sciences Unit University of Cambridge Cambridge UK
                [ 2 ] Centre for Emotional Health Macquarie University Sydney NSW Australia
                [ 3 ] Cambridge University Hospitals NHS Foundation Trust Cambridge UK
                [ 4 ] Department of Psychology Anglia Ruskin University Cambridge UK
                [ 5 ] Institute of Psychiatry, Psychology and Neuroscience King's College London London UK
                [ 6 ] Cambridgeshire and Peterborough NHS Foundation Trust Cambridge UK
                [ 7 ] Department of Clinical Psychology Norwich Medical School University of East Anglia Norwich UK
                Author notes
                [*] [* ] Correspondence

                Caitlin Hitchcock, MRC Cognition and Brain Sciences Unit, University of Cambridge, 15 Chaucer Road, Cambridge, CB2 7EF, UK; Email: Caitlin.Hitchcock@ 123456mrc-cbu.cam.ac.uk

                Author information
                https://orcid.org/0000-0002-0262-623X
                https://orcid.org/0000-0002-2435-0713
                Article
                JCPP13240
                10.1111/jcpp.13240
                7984249
                32343370
                223e616b-4465-4b87-85ff-e8f8ad53f2f3
                © 2020 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 26 February 2020
                Page count
                Figures: 0, Tables: 2, Pages: 7, Words: 6186
                Funding
                Funded by: Economic and Social Research Council , open-funder-registry 10.13039/501100000269;
                Award ID: ES/R010781/1
                Funded by: Medical Research Council (MRC) Clinician Scientist Fellowship
                Award ID: G0802821
                Funded by: National Institute for Health Research Cambridge Biomedical Research Centre
                Funded by: Wellcome Trust
                Award ID: 104908/Z/14/Z
                Award ID: 107496/Z/15/Z
                Funded by: UK Medical Research Council
                Award ID: SUAG/043 G101400
                Categories
                Original Article
                Original Article
                Custom metadata
                2.0
                March 2021
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.0.0 mode:remove_FC converted:22.03.2021

                Clinical Psychology & Psychiatry
                post‐traumatic stress disorder,child,adolescent,trauma,complex ptsd,international classification of diseases

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