- Record: found
- Abstract: found
- Article: not found
Lamotrigine as add-on treatment to lithium and divalproex: lessons learned from a double-blind, placebo-controlled trial in rapid-cycling bipolar disorder.
David E Kemp
1 ,
Keming Gao ,
Elizabeth B Fein ,
Philip K Chan ,
Carla Conroy ,
Sarah Obral ,
Stephen J Ganocy ,
Joseph R Calabrese
Nov 2012
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
A substantial portion of the morbidity associated with rapid-cycling bipolar disorder (RCBD) stems from refractory depression. This study assessed the antidepressant effects of lamotrigine as compared with placebo when used as add-on therapy for rapid-cycling bipolar depression non-responsive to the combination of lithium plus divalproex.