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      2018 Korean Liver Cancer Association–National Cancer Center Korea Practice Guidelines for the Management of Hepatocellular Carcinoma

      review-article
      Author(s): Korean Liver Cancer Association (KLCA) , National Cancer Center (NCC), Goyang, Korea
      Publication date (Electronic):
      Journal: Korean Journal of Radiology
      Publisher: The Korean Society of Radiology
      Keywords: Diagnosis, Guidelines, Carcinoma, hepatocellular, Management

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          Abstract

          Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection is high in middle-aged and elderly patients. These practice guidelines will provide useful and constructive advice for the clinical management of patients with HCC. A total of 44 experts in hepatology, oncology, surgery, radiology, and radiation oncology in the Korean Liver Cancer Association-National Cancer Center Korea Practice Guideline Revision Committee revised the 2014 Korean guidelines and developed new recommendations that integrate the most up-to-date research findings and expert opinions.

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          Most cited references599

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          Management of hepatocellular carcinoma.

          Jordi Bruix, Morris Sherman (2005)
          Article 0 comments Cited 1332 times – based on 0 reviews     Review now
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            Transection of the oesophagus for bleeding oesophageal varices.

            I Lyon, Graeme I Murray, Brenda V. Dawson … (1973)
            Article 0 comments Cited 511 times – based on 0 reviews     Review now
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              Global patterns of hepatocellular carcinoma management from diagnosis to death: the BRIDGE Study

              Joong-Won Park, Minshan Chen, Massimo Colombo … (2015)
              Background & Aims Hepatocellular carcinoma (HCC) is the second most common cause of cancer deaths worldwide. The global HCC BRIDGE study was a multiregional, large-scale, longitudinal cohort study undertaken to improve understanding of real-life management of patients with HCC, from diagnosis to death. Methods Data were collected retrospectively from January 2005 to September 2012 by chart reviews of eligible patients newly diagnosed with HCC at participating institutions. Results Forty-two sites in 14 countries contributed final data for 18 031 patients. Asia accounted for 67% of patients, Europe for 20% and North America for 13%. As expected, the most common risk factor was hepatitis C virus in North America, Europe and Japan, and hepatitis B virus in China, South Korea and Taiwan. The most common Barcelona Clinic Liver Cancer stage at diagnosis was C in North America, Europe, China and South Korea, and A in Taiwan and Japan. Across all stages, first HCC treatment was most frequently transarterial chemoembolization in North America, Europe, China and South Korea, percutaneous ethanol injection or radiofrequency ablation in Japan and resection in Taiwan. Survival from first HCC treatment varied significantly by region, with median overall survival not reached for Taiwan and 60, 33, 31, 24 and 23 months for Japan, North America, South Korea, Europe and China respectively (P < 0.0001). Conclusions Initial results from the BRIDGE study confirm previously reported regional trends in patient demographic characteristics and HCC risk factors, document the heterogeneity of treatment approaches across regions/countries and underscore the need for earlier HCC diagnosis worldwide.
              Article 0 comments Cited 505 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Korean J Radiol
                Journal ID (iso-abbrev): Korean J Radiol
                Journal ID (publisher-id): KJR
                Title: Korean Journal of Radiology
                Publisher: The Korean Society of Radiology
                ISSN (Print): 1229-6929
                ISSN (Electronic): 2005-8330
                Publication date (Print): July 2019
                Publication date (Electronic): 25 June 2019
                Volume: 20
                Issue: 7
                Pages: 1042-1113
                Author notes
                Corresponding author: Korean Liver Cancer Association *-National Cancer Center, Korea †, Practice Guideline Revision Committee. *Korean Liver Cancer Association, 1527 Gangnam Finance Plaza, 419 Teheran-ro, Gangnam-gu, Seoul 06160, Korea. Tel: (822) 313-1900, Fax: (822) 539-5410, klca@ 123456livercancer.or.kr †Center for Liver Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang 10408, Korea. Tel: (8231) 920-1605, Fax: (8231) 920-1520, jwpark@ 123456ncc.re.kr
                Article
                DOI: 10.3348/kjr.2019.0140
                PMC ID: 6609431
                PubMed ID: 31270974
                SO-VID: 19543481-3b5d-4860-9e9f-36c94054011a
                Copyright © Copyright © 2019 The Korean Society of Radiology
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 19 February 2019
                Date accepted : 24 February 2019
                Funding
                Funded by: National Cancer Center, CrossRef https://doi.org/10.13039/501100003645;
                Award ID: 1731510-1
                Categories
                Subject: Gastrointestinal Imaging
                Subject: Review Article

                ScienceOpen disciplines: Radiology & Imaging
                Keywords: diagnosis,guidelines,carcinoma, hepatocellular,management
                Data availability:
                ScienceOpen disciplines: Radiology & Imaging
                Keywords: diagnosis, guidelines, carcinoma, hepatocellular, management

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