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      Cardiovascular Disease and Breast Cancer : Exploring 2 Interconnected Landscapes

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      Author(s): , PhD, RN, MPH a , , MD, MPH b , ∗
      Publication date (Electronic):
      Journal: JACC: CardioOncology
      Publisher: Elsevier
      Keywords: breast cancer, cardio-oncology, heart disease

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          Current and future burden of breast cancer: Global statistics for 2020 and 2040

          Melina Arnold, Eileen Morgan, Harriet Rumgay … (2022)
          Background Breast cancer is the most commonly diagnosed cancer worldwide, and its burden has been rising over the past decades. In this article, we examine and describe the global burden of breast cancer in 2020 and predictions for the year 2040. Methods Estimates of new female breast cancer cases and deaths in 2020 were abstracted from the GLOBOCAN database. Age-standardized incidence and mortality rates were calculated per 100,000 females by country, world region, and level of human development. Predicted cases and deaths were computed based on global demographic projections for the year 2040. Results Over 2.3 million new cases and 685,000 deaths from breast cancer occurred in 2020. Large geographic variation across countries and world regions exists, with incidence rates ranging from <40 per 100,000 females in some Asian and African countries, to over 80 per 100,000 in Australia/New Zealand, Northern America, and parts of Europe. Smaller geographical variation was observed for mortality; however, transitioning countries continue to carry a disproportionate share of breast cancer deaths relative to transitioned countries. By 2040, the burden from breast cancer is predicted to increase to over 3 million new cases and 1 million deaths every year because of population growth and ageing alone. Conclusion Breast cancer is the most common cancer worldwide and continues to have a large impact on the global number of cancer deaths. Global efforts are needed to counteract its growing burden, especially in transitioning countries where incidence is rising rapidly, and mortality rates remain high. • With over 2.3 million new cases and 685,000 deaths in 2020, breast cancer is the most commonly diagnosed cancer worldwide. • Most cases occur in transitioned countries yet transitioning countries have disproportionate share of breast cancer deaths. • The future burden of breast cancer is predicted to increase to over 3 million new cases and 1 million deaths in 2040.
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            2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary

            Donna K. Arnett, Roger S. Blumenthal, Michelle A Albert … (2019)
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              Cardiovascular Disease and Breast Cancer: Where These Entities Intersect: A Scientific Statement From the American Heart Association

              Laxmi S Mehta, Karol Watson, Ana Barac … (2018)
              Cardiovascular disease (CVD) remains the leading cause of mortality in women, yet many people perceive breast cancer to be the number one threat to women's health. CVD and breast cancer have several overlapping risk factors, such as obesity and smoking. Additionally, current breast cancer treatments can have a negative impact on cardiovascular health (eg, left ventricular dysfunction, accelerated CVD), and for women with pre-existing CVD, this might influence cancer treatment decisions by both the patient and the provider. Improvements in early detection and treatment of breast cancer have led to an increasing number of breast cancer survivors who are at risk of long-term cardiac complications from cancer treatments. For older women, CVD poses a greater mortality threat than breast cancer itself. This is the first scientific statement from the American Heart Association on CVD and breast cancer. This document will provide a comprehensive overview of the prevalence of these diseases, shared risk factors, the cardiotoxic effects of therapy, and the prevention and treatment of CVD in breast cancer patients.
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                Author and article information

                Contributors
                Véronique L. Roger
                Journal
                Journal ID (nlm-ta): JACC CardioOncol
                Journal ID (iso-abbrev): JACC CardioOncol
                Title: JACC: CardioOncology
                Publisher: Elsevier
                ISSN (Electronic): 2666-0873
                Publication date PMC-release: 17 December 2024
                Publication date Collection: December 2024
                Publication date (Electronic): 17 December 2024
                Volume: 6
                Issue: 6
                Pages: 904-906
                Affiliations
                [a ]Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
                [b ]Epidemiology and Community Health Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
                Author notes
                [∗ ] Address for correspondence: Dr Véronique L. Roger, National Institutes of Health, National Heart Lung and Blood Institute, 10 Center Drive, BG 10, Bethesda, Maryland 20814, USA. veronique.roger@ 123456nih.gov
                Article
                Publisher Item ID: S2666-0873(24)00363-6
                DOI: 10.1016/j.jaccao.2024.10.008
                PMC ID: 11711825
                SO-VID: 18d8f76c-e967-45ae-9ad5-bb2fb27571ce
                Copyright © © 2024 The Authors
                License:

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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                Categories
                Subject: Mini-Focus Issue: Heart Disease in Women
                Subject: Editorial Comment

                Keywords: breast cancer,cardio-oncology,heart disease
                Data availability:
                Keywords: breast cancer, cardio-oncology, heart disease

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