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      Infecção pelo HIV em jovens: prevalência e fatores associados Translated title: HIV infections in youth: prevalence and associated factors

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          Abstract

          RESUMO Objetivo estimar a prevalência e fatores associados à infecção pelo Human Immunodeficiency Virus (HIV) em jovens. Métodos estudo transversal, realizado em dois Centros de Testagem e Aconselhamento, com 279 jovens entre 15 e 24 anos. Realizou-se teste anti-HIV e aplicou-se instrumento estruturado. Empregaram-se análise bivariada e regressão logística com correção de Bonferroni para investigar a associação entre as variáveis e o desfecho sorológico. Resultados a prevalência de HIV entre os jovens foi de 3,9% (Intervalo de confiança-IC95%: 1,0-10,1). A associação com o desfecho HIV mostrou-se estatisticamente significante entre jovens do sexo masculino (p=0,001), homossexuais (p<0,001), exposição sexual como motivo do teste (p=0,034), percepção de alto de risco de adquirir HIV (p=0,002) e prática de sexo anal (p=0,004). Jovens homossexuais (Odds ratio-OR=13,46; IC95%:1,14-15,84) e com percepção de alto risco de adquirir o HIV (OR=18,11; IC95%: 2,28-143,69) tiveram maiores chances de apresentarem resultado positivo para HIV. Conclusão foi possível identificar a prevalência e fatores associados ao HIV em jovens. Contribuições para a prática: as informações geradas podem disponibilizar evidências aos formuladores de políticas, gestores e profissionais de saúde, e subsidiar a elaboração de estratégias que contemplem o aperfeiçoamento das ações de prevenção, coordenadas e ajustadas aos contextos comportamentais nos cenários estudados.

          Translated abstract

          ABSTRACT Objective to estimate the prevalence and associated factors with Human Immunodeficiency Virus (HIV) infection in youths. Methods cross-sectional study in two Centers for Testing and Counseling, with 279 youths from 15 to 24 years old. An anti-HIV test and a structured instrument were applied. We used bivariate analysis and logistic regression, with Bonferroni corrections, to investigate the association between the variables and the outcome. Results the prevalence of HIV in the youth analyzed was 3.9% (Confidence interval - CI95%: 1.0-10.1). The association with the outcome of HIV was statistically significant in male youth (p=0.001), homosexuals (p<0.001), those who tested due to sexual exposure (p=0.034), perception of a high risk of acquiring HIV (p=0.002), and anal sex (p=0.004). Homosexual youth (odds ratio-OR=13.46; CI95%;1.14-15.84), with a perception of high risk of acquiring HIV (OR=18.11; CI95%: 2.28-143.69) had a higher chance of being HIV positive. Conclusion the prevalence of HIV and associated factors in youth was ascertained. Contributions to practice: the information produced here shows evidence for those who aim to formulate policies, including health managers and workers. It can give support to the elaboration of strategies that involve perfecting preventive, coordinated actions, adjusted to behavioral contexts in the settings studied.

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          How heterogeneous are MSM from Brazilian cities? An analysis of sexual behavior and perceived risk and a description of trends in awareness and willingness to use pre-exposure prophylaxis

          Background Brazil has the largest population of individuals living with HIV/AIDS in Latin America, with a disproportional prevalence of infection among gays, bisexuals and other men who have sex with men (MSM). Of relevance to prevention and treatment efforts, Brazilian MSM from different regions may differ in behaviors and risk perception related to HIV. Methods We report on MSM living in 29 different cities: 26 Brazilian state capitals, the Federal District and two large cities in São Paulo state assessed in three web-based surveys (2016–2018) advertised on Grindr, Hornet and Facebook. Using logistic regression models, we assessed the association of risk behavior with HIV perceived risk as well as factors associated with high-risk behavior. Results A total of 16,667 MSM completed the survey. Overall, MSM from the North and Northeast were younger, more black/mixed-black, of lower income and lower education compared to MSM from the South, Southeast and Central-west. Though 17% had never tested for HIV (with higher percentages in the North and Northeast), condomless receptive anal sex (previous 6 months) and high-risk behavior as per HIV Incidence Risk scale for MSM were observed for 41 and 64%, respectively. Sexual behavior and HIV perceived risk had low variability by city and high-risk behavior was strongly associated with high HIV perceived risk. Younger age, being gay/homosexual, having a steady partner, binge drinking, report of sexually transmitted infection (STI) and ever testing for HIV were associated with increased odds of high-risk behavior. Awareness and willingness to use PrEP increased from 2016 to 2018 in most cities. Conclusions Overall, MSM socio-demographic characteristics were heterogeneous among Brazilian cities, but similarities were noted among the cities from the same administrative region with a marked exception of the Federal District not following the patterns for the Central-West. Combination HIV prevention is most needed among young men who self-identify as gay/homosexual, report binge drinking or prior STI.
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            HIV risk, risk perception and uptake of HIV testing and counseling among youth men who have sex with men attending a gay sauna

            Background Men who have sex with men (MSM) are amongst populations at-risk for HIV acquisition in Thailand. In youth MSM (aged 15–24 years), the incidence of HIV infection has substantially increased. However, data on HIV risk, risk perception and HIV testing and counseling (HTC) uptake among youth MSM in hotspots are limited. Methods A subanalysis of a prospective study among Thai MSM attending a gay sauna was conducted. HIV risk and risk perception were assessed by an anonymous survey. The MSM were categorized as having actual “low-risk”, “moderate-risk” and “high-risk” for HIV acquisition based on the validated study risk categorization tool. HTC was provided on-site with result notification within 1 h. HIV care establishment appointment was arranged by the counselors for HIV-infected participants. Care engagement within 1 year of diagnosis was subsequently assessed. Results There were 358 MSM participants; 87 (24%) were youth MSM. Comparing to other MSM, youth MSM had significantly higher median number of lifetime sexual partners [2 (IQR 1–9) vs. 1 (IQR 0–1); P < 0.001), were more-likely to ever exchange sex for money (44% vs. 9%; P < 0.001) and have sexual partner who exchanged sex for money (8% vs. 1%; P < 0.001). Rates of consistent condom use in the past 3 months for anal, oral and vaginal sexes were low and not significantly different between youth and other MSM (51% vs. 61%, 26% vs. 35% and 72% vs. 61%, respectively). By using the study risk categorization tool, there were 68 youth MSM with moderate or high-risk for HIV acquisition, of which 43 (63%) had false perception of low HIV risk. Youth MSM were more likely than other MSM to accept HTC [68% vs. 33%, P < 0.001)] and to be first-time testers (42% vs. 28%, P = 0.07). By HTC, the rates of HIV infection tended to be higher among youth MSM comparing to other MSM [14/59 (24%) vs. 11/89 (12%); P = 0.07]. Among the 14 youth MSM newly-diagnosed with HIV infection, only 6 (43%) showed-up for continuity care after 1-year follow-up. Conclusions Youth MSM had substantial high HIV risk, false perception of low HIV risk and low rate of care engagement but demonstrated considerable rate of HTC uptake. Strategies to improve access to HTC, risk perception and linkage to care are needed for HIV prevention and management among the youth MSM.
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              HIV incidence is rapidly increasing with age among young men who have sex with men in China: a multicentre cross‐sectional survey

              Objectives The HIV epidemic is worsening among men who have sex with men (MSM) in China, especially among those who are younger than 25 years old [younger MSM (YMSM)]. The aim of the study was to compare the prevalences of HIV incidence and recent HIV infection as well as factors associated with recent HIV infection in YMSM and older MSM (OMSM). Methods A multicentre cross‐sectional survey was conducted among 4496 MSM recruited from seven Chinese cities. YMSM were defined as those aged < 25 years. Data on demographics and sexual behaviours were collected using structural questionnaires. Blood samples were tested for recent HIV infection and other sexually transmitted infections. Results Among the participants, 1313 were YMSM and 3183 were OMSM. Compared with OMSM, YMSM had a higher prevalence of recent HIV infection [5.4% (71 of 1313) for YMSM vs. 3.6% (115 of 3175) for OMSM; P = 0.006] and a higher HIV incidence [11.8 per 100 person‐years (PY) (95% confidence interval (CI) 9.0–14.5) for YMSM vs. 7.6 per 100 PY (95% CI 6.3–9.0) for OMSM]. The incidence increased with age among YMSM, especially between the ages of 16 and 21 years. In contrast, the incidence declined with age among OMSM. Anal bleeding, recreational drug use, syphilis and herpes simplex virus 2 (HSV‐2) infection were independent risk factors for recent HIV infection among YMSM. The prevalence of all these risk factors increased with age between the ages of 16 and 21 years. Anal bleeding (19.8%) and recreational drug use (19.5%) had the highest adjusted population attributable fractions (aPAFs) among YMSM. The highest aPAFs of anal bleeding (27.4%) and syphilis infection (25.5%) were found between the ages of 19 and 21 years. Conclusions The HIV incidence in Chinese YMSM was significantly higher than that in OMSM. YMSM aged 16–21 years had an extremely high risk of recent HIV infection.
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                Author and article information

                Journal
                rene
                Rev Rene
                Rev. Rene
                Universidade Federal do Ceará (Fortaleza, CE, Brazil )
                1517-3852
                2175-6783
                2023
                : 24
                : e83018
                Affiliations
                [2] Campina Grande Paraíba orgnameUniversidade Federal de Campina Grande Brazil
                [1] João Pessoa orgnameUniversidade Federal da Paraíba Brazil
                Article
                S1517-38522023000100313 S1517-3852(23)02400000313
                10.15253/2175-6783.20232483018
                1850efff-3194-4d7d-95fd-ef2feb6a27e6

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 14 December 2022
                : 20 March 2023
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 30, Pages: 0
                Product

                SciELO Revista de Enfermagem

                Categories
                Artigos Originais

                Health Risk Behaviors,HIV Seroprevalence,Adolescent Behavior,Young Adult,Cross-Sectional Studies,Soroprevalência de HIV,Comportamento do Adolescente,Adulto Jovem,Comportamentos de Risco à Saúde,Estudos Transversais

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