The effect of breast-feeding duration on bone mineral density in postmenopausal Turkish women: a population-based study

Abstract

Introduction

In the present study, we investigated the effects of breast-feeding time on bone mineral density (BMD) later in life.

Material and methods

The current study was based on a retrospective analysis of 586 postmenopausal women with a mean age of 60.8 years, who were screened for osteoporosis by dual energy X-ray absorptiometry (DXA).They were classified into 4 groups with respect to the duration of their breast-feeding as never (group 1), 1-24 months (group 2), 25-60 months (group 3), or > 60 months (group 4). Bone mineral density results for the femur neck and lumbar spine were classified into 3 groups according to WHO criteria as normal ( T score > –1.0 SD), osteopenia ( T score –1.0 to –2.5 SD), and osteoporosis ( T score < –2.5 SD). Patients with osteopenia or osteoporosis ( T score < –1.0 SD) were considered as having low bone mass (LBM).

Results

We found a correlation between duration of lactation and femur BMD or spine BMD in the study population ( r = 0.116, p < 0.005; r = –0.151, p = 0.001, respectively). Significant differences were found between femur BMD and spine BMD of groups in one-way ANOVA analysis ( p = 0.025, p = 0.005, respectively). Additionally, when compared with the other three groups, group 4 was older and had longer duration of menopause ( p < 0.01). In logistic regression analysis, age and body mass index were found as independent risk factors of LBM [odds ratio: 1.084 (95% CI 1.031-1.141); odds ratio: 0.896 (95% CI 0.859-0.935)], while duration of lactation was not found as an independent predictor of LBM.

Conclusions

In this study, we have found that changes of bone metabolism during lactation had no effect on postmenopausal BMD measured by DXA. Consequently, it can be suggested that long breast-feeding duration is not a risk factor for low bone mass later in life.