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      High revision rates and mortality after distal femoral replacement for periprosthetic distal femoral fractures: analysis from the German Arthroplasty Registry (EPRD)

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          Abstract

          Purpose

          This study was initiated to analyze the outcome after distal femoral replacement (DFR) for periprosthetic distal femoral fractures (PDFF).

          Methods

          Data from the German Arthroplasty Registry (EPRD) were analyzed. A total of 626 patients could be identified with a DFR for PDFF. Mean age was 78.8 years, and 84.2% were female. Revisions and mortality were analyzed and compared with patient groups with a similar procedure (revision total knee arthroplasty) or similar general condition (fracture total hip arthroplasty, hip hemiarthroplasty). Matched-pair-analyses were performed.

          Results

          Within one year after surgery, 13.2% of the patients had died and further 9.4% were revised. Within four years, 32.7% had died and 19.7% were revised. Revisions were nearly twice as high as in the comparison groups. Periprosthetic infection (PJI) was the most frequent cause for revision, resulting in a PJI rate of 12.8%, which was lower in the comparison groups. Mortality after DFR was as similar high as after fracture hip arthroplasty.

          Conclusion

          PDFF are a serious injury, and the necessary surgical treatment has a high risk of complications. Every third patient after DFR for PDFF had died and every fifth patient needed revision within 4 years after surgery. Efforts should be undertaken to provide optimal treatment to these high-risk patients to reduce unfavorable outcomes.

          Level of evidence

          III.

          Registration of clinical trials

          As this is a registry-derived study of data of the German Arthroplasty Registry (EPRD), no registration was performed.

          Related collections

          Most cited references20

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          Mortality after periprosthetic fracture of the femur.

          Management of periprosthetic femoral fractures is often complex, and few studies have documented its associated mortality. We retrospectively identified from our trauma and surgical registries 106 patients who underwent surgery for a periprosthetic femoral fracture. We then identified a contemporaneous age and sex-matched control cohort of 309 patients who had a hip fracture (femoral neck or intertrochanteric) and 311 patients who underwent primary hip or knee replacement. Mortality at one year was identified with use of the Social Security database. Twelve (11%) of 106 patients died within one year following surgical treatment of a periprosthetic fracture. During the same follow-up period, fifty-one (16.5%) of 309 patients died following surgery for a hip fracture and nine (2.9%) of 311 patients died following primary joint replacement. The mortality rate after a periprosthetic femoral fracture was significantly higher (p < 0.0001) compared with that for matched patients who had undergone primary joint replacement, and it was similar to the mortality rate after a hip fracture. For periprosthetic fractures, a delay of greater than two days from admission to the time of surgery was associated with an increased mortality rate at one year (p < 0.0007). Forty-nine patients underwent revision arthroplasty for the treatment of a Vancouver type-B periprosthetic fracture, and six (12%) died. In contrast, twenty-four patients with a Vancouver type-B periprosthetic fracture were treated with open reduction and internal fixation and eight (33%) died. The difference was significant (p < 0.03). The mortality rate within one year following surgical treatment of periprosthetic femoral fractures is high and is similar to that after treatment for hip fractures. Because revision arthroplasty for the treatment of type-B periprosthetic fractures was associated with a one-year mortality rate that was significantly less than that after surgical treatment with open reduction and internal fixation, in instances when either treatment option is feasible, revision arthroplasty may be the preferred option.
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            Population-based epidemiology and incidence of distal femur fractures.

            The literature lacks recent epidemiological studies on the incidence, trauma mechanism and fracture classification of distal femur fractures. The aim of the present study was to provide up-to-date information concerning the incidence of distal femur fractures in a large and complete population and to report on the distribution of fracture classification, trauma mechanisms and patient baseline demographics.
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              • Abstract: found
              • Article: not found

              Geriatric distal femur fracture: Are we underestimating the rate of local and systemic complications?

              Low energy distal femur fractures often occur in a fragile elderly population that is prone to local and systemic complications following operative treatment of extremity fractures. The nonunion rate and early complication rate following laterally based locked plating in this specific fracture are not well described.
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                Author and article information

                Contributors
                Joerg.Luetzner@freenet.de
                Journal
                Eur J Orthop Surg Traumatol
                Eur J Orthop Surg Traumatol
                European Journal of Orthopaedic Surgery & Traumatology
                Springer Paris (Paris )
                1633-8065
                1432-1068
                27 July 2023
                27 July 2023
                2024
                : 34
                : 1
                : 331-338
                Affiliations
                [1 ]GRID grid.4488.0, ISNI 0000 0001 2111 7257, University Center of Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, , TU Dresden, ; Dresden, Germany
                [2 ]German Arthroplasty Registry (EPRD), Berlin, Germany
                [3 ]Center for Orthopaedic Surgery, Augsburg, Germany
                Author information
                http://orcid.org/0000-0002-7162-828X
                http://orcid.org/0000-0001-8291-7012
                http://orcid.org/0000-0002-4022-2172
                http://orcid.org/0000-0001-6616-4444
                Article
                3582
                10.1007/s00590-023-03582-2
                10771596
                37498352
                10ab8e70-8983-47ae-91df-95c2e2715c09
                © The Author(s) 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 26 April 2023
                : 10 May 2023
                Funding
                Funded by: German Arthroplasty Registry (EPRD)
                Funded by: Technische Universität Dresden (1019)
                Categories
                Original Article
                Custom metadata
                © Springer-Verlag France SAS, part of Springer Nature 2024

                Orthopedics
                periprosthetic distal femur fracture,tka,tkr,distal femoral replacement,mortality,revision
                Orthopedics
                periprosthetic distal femur fracture, tka, tkr, distal femoral replacement, mortality, revision

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