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Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin.
Paula Tejera
1 ,
Nuala J Meyer ,
Feng Chen ,
Rui Feng ,
Yang Zhao ,
D Shane O'Mahony ,
Lin Li ,
Chau-Chyun Sheu ,
Rihong Zhai ,
Zhaoxi Wang ,
Li Su ,
Ed Bajwa ,
Amy M Ahasic ,
Peter F Clardy ,
Michelle N Gong ,
Angela J Frank ,
Paul N Lanken ,
B Taylor Thompson ,
Jason D Christie ,
Mark M Wurfel ,
Grant E O'Keefe ,
David C Christiani
Nov 2012
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Abstract
The role of genetics in the development of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) from direct or indirect lung injury has not been specifically investigated. The aim of this study was to identify genetic variants contributing to ALI/ARDS from pulmonary or extrapulmonary causes.