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      UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants

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          Abstract

          Bronchiolitis is an acute respiratory illness that is the leading cause of hospitalization in young children. This document aims to update the consensus document published in 2014 to provide guidance on the current best practices for managing bronchiolitis in infants . The document addresses care in both hospitals and primary care. The diagnosis of bronchiolitis is based on the clinical history and physical examination. The mainstays of management are largely supportive, consisting of fluid management and respiratory support. Evidence suggests no benefit with the use of salbutamol, glucocorticosteroids and antibiotics with potential risk of harm. Because of the lack of effective treatment, the reduction of morbidity must rely on preventive measures. De-implementation of non-evidence-based interventions is a major goal, and educational interventions for clinicians should be carried out to promote high-value care of infants with bronchiolitis. Well-prepared implementation strategies to standardize care and improve the quality of care are needed to promote adherence to guidelines and discourage non-evidence-based attitudes. In parallel, parents' education will help reduce patient pressure and contribute to inappropriate prescriptions. Infants with pre-existing risk factors (i.e., prematurity, bronchopulmonary dysplasia, congenital heart diseases, immunodeficiency, neuromuscular diseases, cystic fibrosis, Down syndrome) present a significant risk of severe bronchiolitis and should be carefully assessed. This revised document, based on international and national scientific evidence, reinforces the current recommendations and integrates the recent advances for optimal care and prevention of acute bronchiolitis.

          Supplementary Information

          The online version contains supplementary material available at 10.1186/s13052-022-01392-6.

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          David Moher and colleagues introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses
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            AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both

            The number of published systematic reviews of studies of healthcare interventions has increased rapidly and these are used extensively for clinical and policy decisions. Systematic reviews are subject to a range of biases and increasingly include non-randomised studies of interventions. It is important that users can distinguish high quality reviews. Many instruments have been designed to evaluate different aspects of reviews, but there are few comprehensive critical appraisal instruments. AMSTAR was developed to evaluate systematic reviews of randomised trials. In this paper, we report on the updating of AMSTAR and its adaptation to enable more detailed assessment of systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. With moves to base more decisions on real world observational evidence we believe that AMSTAR 2 will assist decision makers in the identification of high quality systematic reviews, including those based on non-randomised studies of healthcare interventions.
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              AGREE II: advancing guideline development, reporting and evaluation in health care.

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                Author and article information

                Contributors
                eugenio.baraldi@unipd.it
                Journal
                Ital J Pediatr
                Ital J Pediatr
                Italian Journal of Pediatrics
                BioMed Central (London )
                1824-7288
                10 February 2023
                10 February 2023
                2023
                : 49
                : 19
                Affiliations
                [1 ]GRID grid.10438.3e, ISNI 0000 0001 2178 8421, University of Messina, ; Messina, Italy
                [2 ]GRID grid.4691.a, ISNI 0000 0001 0790 385X, SIP “Società Italiana di Pediatria”, , University “Federico II”, ; Naples, Italy
                [3 ]GRID grid.476687.c, ISNI 0000 0001 0944 2874, SIN “Società Italiana di Neonatologia”, , Hospital San Giovanni Calibita Fatebenefratelli, ; Rome, Italy
                [4 ]GRID grid.7841.a, SIMRI ”Società Italiana per le Malattie Respiratorie Infantili”, , University of Rome “La Sapienza”, ; Rome, Italy
                [5 ]GRID grid.419425.f, ISNI 0000 0004 1760 3027, SIAIP “Società Italiana di Allergologia e Immunologia Pediatrica”, , Foundation IRCCS Policlinico San Matteo, ; Pavia, Italy
                [6 ]AMIETIP ”Accademia Medica Infermieristica di Emergenza e Terapia Intensiva Pediatrica”, Major Hospital Polyclinic: Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Bologna, Italy
                [7 ]SIMEUP “Società Italiana di Medicina di Emergenza ed Urgenza Pediatrica”, Pugliese Ciaccio Hospital, Catanzaro, Italy
                [8 ]SIMP “Società Italiana di Medicina Perinatale”, University Hospital of Ancona Umberto I G M Lancisi G Salesi, Ancona, Italy
                [9 ]SICP “Società Italiana di Cardiologia Pediatrica”, University Hospital Meyer, Firenze, Italy
                [10 ]GRID grid.8158.4, ISNI 0000 0004 1757 1969, SINP “Società Italiana di Neurologia Pediatrica”, , University of Catania, ; Catania, Italy
                [11 ]GRID grid.415069.f, ISNI 0000 0004 1808 170X, SIPO “Società Italiana Pediatria Ospedaliera”, , San Giuseppe Moscati Hospital, ; Aversa, Italy
                [12 ]SIPPS “Società Italiana di Pediatria Preventiva e Sociale”, Local Health Authority Caserta, Caserta, Italy
                [13 ]GRID grid.414125.7, ISNI 0000 0001 0727 6809, SITIP “Società Italiana di Infettivologia Pediatrica”, , Bambino Gesu Pediatric Hospital, ; Rome, Italy
                [14 ]FIMP “Federazione Italiana Medici Pediatri”, Local Health Authority Naples 1 Centre, Naples, Italy
                [15 ]SICuPP “Società Italiana delle Cure Primarie Pediatriche”, Florence City Council, Florence, Italy
                [16 ]GRID grid.412311.4, AIEOP “Società Italiana di Ematologia e Oncologia Pediatrica”, , IRCCS University Hospital of Bologna, ; Bologna, Italy
                [17 ]GRID grid.411075.6, ISNI 0000 0004 1760 4193, SIMGePeD “Società Italiana Malattie Genetiche Pediatriche e Disabilità Congenite”, , University Hospital Agostino Gemelli, ; Rome, Italy
                [18 ]GRID grid.6292.f, ISNI 0000 0004 1757 1758, Alma Mater Studiorum University of Bologna, ; Bologna, Italy
                [19 ]GRID grid.411475.2, ISNI 0000 0004 1756 948X, University Hospital of Verona, ; Verona, Italy
                [20 ]GRID grid.417165.0, ISNI 0000 0004 1759 6939, Ospedale Degli Infermi, ; Biella, Italy
                [21 ]GRID grid.7605.4, ISNI 0000 0001 2336 6580, University of Turin, ; Turin, Italy
                [22 ]GRID grid.10383.39, ISNI 0000 0004 1758 0937, University of Parma, ; Parma, Italy
                [23 ]GRID grid.10776.37, ISNI 0000 0004 1762 5517, University of Palermo, ; Palermo, Italy
                [24 ]GRID grid.411474.3, ISNI 0000 0004 1760 2630, Department of Women’s and Children’s Health, Neonatal Intensive Care Unit, , University Hospital of Padova, ; Padova, Italy
                Article
                1392
                10.1186/s13052-022-01392-6
                9912214
                36765418
                07334f20-4957-43e8-8175-abf264d01f13
                © The Author(s) 2023

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 17 November 2022
                : 29 November 2022
                Categories
                Review
                Custom metadata
                © The Author(s) 2023

                Pediatrics
                bronchiolitis,guidelines,infants,respiratory syncytial virus,update,prevention
                Pediatrics
                bronchiolitis, guidelines, infants, respiratory syncytial virus, update, prevention

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