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Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial
Daimin Wei ,
Jia-Yin Liu ,
Yun Sun ,
Yuhua Shi ,
Bo Zhang ,
Jian-Qiao Liu ,
Jichun Tan ,
Xiaoyan Liang ,
Yunxia Cao ,
Ze Wang ,
Yingying Qin ,
Han Zhao ,
Yi Zhou ,
Haiqin Ren ,
Guimin Hao ,
Xiufeng Ling ,
Junzhao Zhao ,
Yunshan Zhang ,
Xiujuan Qi ,
Lin Zhang ,
Xiaohui Deng ,
Xiaoli Chen ,
Yimin Zhu ,
Xiaohong Wang ,
Li-Feng Tian ,
Qun Lv ,
Xiang Ma ,
Heping Zhang ,
Richard S Legro ,
Zi-Jiang Chen
February 2019
February 2019
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Abstract
Elective single embryo transfer (eSET) has been increasingly advocated, but concerns
about the lower pregnancy rate after reducing the number of embryos transferred have
encouraged transfer of multiple embryos. Extended embryo culture combined with electively
freezing all embryos and undertaking a deferred frozen embryo transfer might increase
pregnancy rate after eSET. We aimed to establish whether elective frozen single blastocyst
transfer improved singleton livebirth rate compared with fresh single blastocyst transfer.