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      Protein nanoparticles in drug delivery: animal protein, plant proteins and protein cages, albumin nanoparticles

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          Abstract

          In this article, we will describe the properties of albumin and its biological functions, types of sources that can be used to produce albumin nanoparticles, methods of producing albumin nanoparticles, its therapeutic applications and the importance of albumin nanoparticles in the production of pharmaceutical formulations. In view of the increasing use of Abraxane and its approval for use in the treatment of several types of cancer and during the final stages of clinical trials for other cancers, to evaluate it and compare its effectiveness with conventional non formulations of chemotherapy Paclitaxel is paid. In this article, we will examine the role and importance of animal proteins in Nano medicine and the various benefits of these biomolecules for the preparation of drug delivery carriers and the characteristics of plant protein Nano carriers and protein Nano cages and their potentials in diagnosis and treatment. Finally, the advantages and disadvantages of protein nanoparticles are mentioned, as well as the methods of production of albumin nanoparticles, its therapeutic applications and the importance of albumin nanoparticles in the production of pharmaceutical formulations.

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          Analysis of nanoparticle delivery to tumours

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            Nano based drug delivery systems: recent developments and future prospects

            Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.) in the treatment of various diseases. The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (e.g., natural products) and selective diagnosis through disease marker molecules. The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed. In addition, we have included information regarding the trends and perspectives in nanomedicine area.
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              Mechanisms of solute release from porous hydrophilic polymers

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                Author and article information

                Contributors
                e-kianfar94@iau-arak.ac.ir , ehsan_kianfar2010@yahoo.com
                Journal
                J Nanobiotechnology
                J Nanobiotechnology
                Journal of Nanobiotechnology
                BioMed Central (London )
                1477-3155
                29 May 2021
                29 May 2021
                2021
                : 19
                : 159
                Affiliations
                [1 ]GRID grid.411739.9, ISNI 0000 0001 2331 2603, ERNAM-Erciyes University Nanotechnology Application and Research Center, ; Kayseri, 38039 Turkey
                [2 ]GRID grid.411739.9, ISNI 0000 0001 2331 2603, Department of Analytical Chemistry, Faculty of Pharmacy, , Erciyes University, ; Kayseri, 38039 Turkey
                Article
                896
                10.1186/s12951-021-00896-3
                8164776
                34051806
                02fb14c8-976e-42dd-8d87-7b1029bdb2c8
                © The Author(s) 2021

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 9 April 2021
                : 12 May 2021
                Categories
                Review
                Custom metadata
                © The Author(s) 2021

                Biotechnology
                protein nanoparticles,drug delivery,animal protein,plant proteins,protein cages,albumin nanoparticles

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