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      Automatic Human Sleep Stage Scoring Using Deep Neural Networks

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          Abstract

          The classification of sleep stages is the first and an important step in the quantitative analysis of polysomnographic recordings. Sleep stage scoring relies heavily on visual pattern recognition by a human expert and is time consuming and subjective. Thus, there is a need for automatic classification. In this work we developed machine learning algorithms for sleep classification: random forest (RF) classification based on features and artificial neural networks (ANNs) working both with features and raw data. We tested our methods in healthy subjects and in patients. Most algorithms yielded good results comparable to human interrater agreement. Our study revealed that deep neural networks (DNNs) working with raw data performed better than feature-based methods. We also demonstrated that taking the local temporal structure of sleep into account a priori is important. Our results demonstrate the utility of neural network architectures for the classification of sleep.

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          Most cited references59

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          Deep visual-semantic alignments for generating image descriptions

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            Convolutional Neural Networks for Speech Recognition

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              Phoneme recognition using time-delay neural networks

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                Author and article information

                Contributors
                Journal
                Front Neurosci
                Front Neurosci
                Front. Neurosci.
                Frontiers in Neuroscience
                Frontiers Media S.A.
                1662-4548
                1662-453X
                06 November 2018
                2018
                : 12
                : 781
                Affiliations
                [1] 1Chronobiology and Sleep Research, Institute of Pharmacology and Toxicology, University of Zurich , Zurich, Switzerland
                [2] 2Neuroscience Center Zurich, University of Zurich and ETH Zurich , Zurich, Switzerland
                [3] 3Center for Interdisciplinary Sleep Research, University of Zurich , Zurich, Switzerland
                [4] 4Information Science and Engineering, Institute for Machine Learning, ETH Zurich , Zurich, Switzerland
                [5] 5Max Planck Institute for Intelligent Systems , Tübingen, Germany
                [6] 6Sensory-Motor Systems Lab, ETH Zurich , Zurich, Switzerland
                [7] 7Sleep Disorders Center, Department of Clinical Neurophysiology, Institute of Psychiatry and Neurology in Warsaw , Warsaw, Poland
                [8] 8Third Department of Psychiatry and Sleep Disorders Center, Institute of Psychiatry and Neurology in Warsaw , Warsaw, Poland
                [9] 9University Hospital Balgrist (SCI Center), Medical Faculty, University of Zurich , Zurich, Switzerland
                Author notes

                Edited by: Michael Lazarus, University of Tsukuba, Japan

                Reviewed by: Ivana Rosenzweig, King’s College London, United Kingdom; Jussi Virkkala, Finnish Institute of Occupational Health, Finland; Alejandro Bassi, Universidad de Chile, Chile

                *Correspondence: Peter Achermann, acherman@ 123456pharma.uzh.ch

                This article was submitted to Sleep and Circadian Rhythms, a section of the journal Frontiers in Neuroscience

                Article
                10.3389/fnins.2018.00781
                6232272
                30459544
                026611b3-9860-4181-b1d8-91586ecda192
                Copyright © 2018 Malafeev, Laptev, Bauer, Omlin, Wierzbicka, Wichniak, Jernajczyk, Riener, Buhmann and Achermann.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 18 July 2018
                : 09 October 2018
                Page count
                Figures: 7, Tables: 0, Equations: 0, References: 89, Pages: 15, Words: 0
                Funding
                Funded by: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 10.13039/501100001711
                Categories
                Neuroscience
                Original Research

                Neurosciences
                deep learning,sleep,eeg,automatic scoring,random forest,artificial neural networks,features,raw data

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