Automatic and Accurate Sleep Stage Classification via a Convolutional Deep Neural Network and Nanomembrane Electrodes.

Abstract

Sleep stage classification is an essential process of diagnosing sleep disorders and related diseases. Automatic sleep stage classification using machine learning has been widely studied due to its higher efficiency compared with manual scoring. Typically, a few polysomnography data are selected as input signals, and human experts label the corresponding sleep stages manually. However, the manual process includes human error and inconsistency in the scoring and stage classification. Here, we present a convolutional neural network (CNN)-based classification method that offers highly accurate, automatic sleep stage detection, validated by a public dataset and new data measured by wearable nanomembrane dry electrodes. First, our study makes a training and validation model using a public dataset with two brain signal and two eye signal channels. Then, we validate this model with a new dataset measured by a set of nanomembrane electrodes. The result of the automatic sleep stage classification shows that our CNN model with multi-taper spectrogram pre-processing achieved 88.85% training accuracy on the validation dataset and 81.52% prediction accuracy on our laboratory dataset. These results validate the reliability of our classification method on the standard polysomnography dataset and the transferability of our CNN model for other datasets measured with the wearable electrodes.