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      Hair dye poisoning and the developing world

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          Abstract

          Hair dye poisoning has been emerging as one of the important causes of intentional self harm in the developing world. Hair dyes contain paraphenylene-diamine and a host of other chemicals that can cause rhabdomyolysis, laryngeal edema, severe metabolic acidosis and acute renal failure. Intervention at the right time has been shown to improve the outcome. In this article, we review the various manifestations, clinical features and treatment modalities for hair dye poisoning.

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          Most cited references18

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          Hair care products: waving, straightening, conditioning, and coloring.

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            Propylene glycol-induced proximal renal tubular cell injury.

            Propylene glycol is a solvent that is used in many oral, injectable, and topical medications. Although uncommon, acute renal failure has been attributed to propylene glycol. The mechanism of propylene glycol-mediated renal injury is unknown. We report a case of acute renal failure in a 16-year-old boy given large doses of pentobarbital and phenobarbital, both of which are solubilized with propylene glycol. A renal biopsy showed proximal renal tubular cell swelling and vacuole formation. The data from this case suggest that the reversible acute renal failure caused by propylene glycol is attributable to proximal renal tubular cell injury.
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              Acute renal failure following para-phenylenediamine (PPD) poisoning: a case report and review.

              We report a case of systemic poisoning with para-phenylenediamine (PPD) presenting with characteristic features of severe angioneurotic edema, rhabdomyolysis and intravascular hemolysis with hemoglobinuria culminating in acute renal failure. Though rare in western countries, such poisoning is not uncommon in East Africa, Indian subcontinent and Middle East countries. We discuss here the clinical features and key management issues of systemic PPD poisoning.
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                Author and article information

                Journal
                J Emerg Trauma Shock
                JETS
                Journal of Emergencies, Trauma and Shock
                Medknow Publications (India )
                0974-2700
                0974-519X
                May-Aug 2009
                : 2
                : 2
                : 129-131
                Affiliations
                Department of Nephrology, Meenakshi Mission Hospital and Research Centre, Lake Area, Melur Road, Madurai, Tamil Nadu - 625 107, India
                Author notes
                Address for correspondence: Dr. Krishnaswamy Sampathkumar, E-mail: drksampath@ 123456gmail.com
                Article
                JETS-02-129
                10.4103/0974-2700.50749
                2700586
                19561974
                3f6fb3af-0158-4d06-98a6-7aed95055b83
                © Journal of Emergencies, Trauma and Shock

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 12 September 2008
                : 16 September 2008
                Categories
                Toxicology Update

                Emergency medicine & Trauma
                paraphenylene diamine,suicide,hair dye poisoning
                Emergency medicine & Trauma
                paraphenylene diamine, suicide, hair dye poisoning

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