1
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Prevalence of syphilis in transgender women and travestis in Brazil: results from a national cross-sectional study Translated title: Prevalência de sífilis em mulheres trans e travestis no Brasil: resultados de um estudo multicêntrico nacional

      research-article

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          ABSTRACT Objective: The study aimed to estimate the prevalence of acquired syphilis and associated factors in a national survey. Methods: TransOdara was a cross-sectional study comprising transgender women and travestis (TGW) in five major cities in Brazil during December of 2019 and July of 2021. The sample was recruited using the respondent-driven sampling (RDS) method. The outcome “active syphilis” was defined as a positive treponemal test and Venereal-Disease-Research-Laboratory (VDRL) title greater than∕ equal to ⅛. Sociodemographic variables were described. Bivariate and multiple logistic regression were performed, and odds ratios (OR) and 95% confidence intervals (95%CI) were estimated. All analyses were performed in R, 4.3.1. Results: A total of 1,317 TGW were recruited, with 1,291 being tested for syphilis, and 294 (22.8%) meeting the criteria for active syphilis. In bivariate analysis, black/mixed race (OR=1.41, 95%CI 1.01–1.97), basic level of education (OR=2.44, 95%CI 1.17–5.06), no name change in documents (OR=1.39, 95%CI 1.00–1.91) and sex work (past only OR= 2.22, 95%CI 1.47–3.32; partial OR=2.75, 95%CI 1.78–4.25; full time OR=3.62, 95%CI 2.36–5.53) were associated with active syphilis. In the multivariate analysis, sex work was the only associated factor, 2.07 (95%CI 1.37–3.13) past sex work, 2.59 (95%CI 1.66–4.05) part-time sex work and 3.16 (95%CI 2.04–4.92) sex work as the main source of income. Conclusion: The prevalence of active syphilis in this study was elevated compared with other countries in Latin America. Sex work was an important associated factor with active syphilis, highlighting the impact that this condition of vulnerability may have in the health of TGW, as members of a key, marginalized population.

          Translated abstract

          RESUMO Objetivo: O estudo teve como objetivo estimar a prevalência de sífilis adquirida e fatores associados em uma pesquisa nacional. Métodos: "TransOdara" foi um estudo transversal compreendendo mulheres trans e travestis (MTT) em cinco grandes cidades do Brasil durante dezembro–2019 e julho–2021. A amostra foi recrutada usando o método respondente-driven sampling (RDS). O desfecho “sífilis ativa” foi definido como um teste treponêmico positivo e título do Venereal-Disease-Research-Laboratory (VDRL) maior ou igual a ⅛. Variáveis sociodemográficas foram descritas. Análises bi- e multivariadas foram realizadas, e odds ratio (OR) e IC95% foram estimados. Todas as análises foram realizadas no R,4.3.1. Resultados: Um total de 1.317 MTT foram recrutadas, com 1.291 sendo testadas para sífilis, das quais 294 (22,8%) preencheram os critérios para sífilis ativa. Na análise bivariada, raça negra/parda (OR=1,41; IC95% 1,01–1,97), nível básico de educação (OR=2,44; IC95% 1,17–5,06), não alteração do nome nos documentos (OR=1,39; IC95% 1,00–1,91) e trabalho sexual (pregresso OR=2,22; IC95% 1,47–3,32; parcial OR=2,75; IC95% 1,78–4,25; período integral OR=3,62; IC95%: 2,36-5,53) foram associados à sífilis ativa. Na análise multivariada, o trabalho sexual foi o único fator associado, 2,07 (IC95%: 1,37-3,13) trabalho sexual passado, 2,59 (IC95% 1,66–4,05) trabalho sexual em tempo parcial e 3,16 (IC95% 2,04–4,92) trabalho sexual como principal fonte de renda. Conclusão: A prevalência de sífilis ativa neste estudo foi elevada em comparação com outros países da América Latina. O trabalho sexual foi um fator associado importante com sífilis ativa, destacando o impacto que essa condição de vulnerabilidade pode ter na saúde das MTT, como membros de uma população-chave marginalizada.

          Related collections

          Most cited references27

          • Record: found
          • Abstract: not found
          • Article: not found

          The Modern Epidemic of Syphilis

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Unveiling of HIV dynamics among transgender women: a respondent-driven sampling study in Rio de Janeiro, Brazil

            The burden of HIV in transgender women (transwomen) in Brazil remains unknown. We aimed to estimate HIV prevalence among transwomen in Rio de Janeiro and to identify predictors of newly diagnosed HIV infections.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              HIV, HCV, HBV, and syphilis among transgender women from Brazil

              Abstract Different sampling strategies, analytic alternatives, and estimators have been proposed to better assess the characteristics of different hard-to-reach populations and their respective infection rates (as well as their sociodemographic characteristics, associated harms, and needs) in the context of studies based on respondent-driven sampling (RDS). Despite several methodological advances and hundreds of empirical studies implemented worldwide, some inchoate findings and methodological challenges remain. The in-depth assessment of the local structure of networks and the performance of the available estimators are particularly relevant when the target populations are sparse and highly stigmatized. In such populations, bottlenecks as well as other sources of biases (for instance, due to homophily and/or too sparse or fragmented groups of individuals) may be frequent, affecting the estimates. In the present study, data were derived from a cross-sectional, multicity RDS study, carried out in 12 Brazilian cities with transgender women (TGW). Overall, infection rates for HIV and syphilis were very high, with some variation between different cities. Notwithstanding, findings are of great concern, considering the fact that female TGW are not only very hard-to-reach but also face deeply-entrenched prejudice and have been out of the reach of most therapeutic and preventive programs and projects. We cross-compared findings adjusted using 2 estimators (the classic estimator usually known as estimator II, originally proposed by Volz and Heckathorn) and a brand new strategy to adjust data generated by RDS, partially based on Bayesian statistics, called for the sake of this paper, the RDS-B estimator. Adjusted prevalence was cross-compared with estimates generated by non-weighted analyses, using what has been called by us a naïve estimator or rough estimates.
                Bookmark

                Author and article information

                Journal
                rbepid
                Revista Brasileira de Epidemiologia
                Rev. bras. epidemiol.
                Associação Brasileira de Saúde Coletiva (São Paulo, SP, Brazil )
                1415-790X
                1980-5497
                2024
                : 27
                : suppl 1
                : e240003.supl.1
                Affiliations
                [1] São Paulo SP orgnameSanta Casa de São Paulo orgdiv1School of Medical Sciences Brazil
                [2] Sydney NSW orgnameWestern Sydney University orgdiv1Translational Health Research Institute Australia
                [3] Manaus AM orgnameFiocruz Amazônia orgdiv1Instituto Leônidas e Maria Deane Brazil
                [4] Los Angeles CA orgnameAids Healthcare Foundation EUA
                [5] São Paulo São Paulo orgnameInstituto Adolfo Lutz Brazil
                [6] Salvador Bahia orgnameUniversidade Federal da Bahia orgdiv1Institute of Public Health Brazil
                Author information
                https://orcid.org/0000-0003-0558-6672
                https://orcid.org/0000-0001-5367-3397
                https://orcid.org/0000-0002-1656-5749
                https://orcid.org/0000-0003-0680-1485
                https://orcid.org/0000-0003-3645-025X
                https://orcid.org/0000-0002-1285-3532
                https://orcid.org/0000-0002-7389-0994
                https://orcid.org/0000-0003-1675-2146
                https://orcid.org/0000-0002-1159-5762
                Article
                S1415-790X2024000200401 S1415-790X(24)02700000401
                10.1590/1980-549720240003.supl.1
                761cbaab-f2bb-4451-83bb-1aa9e739753c

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 14 November 2023
                : 11 March 2024
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 23, Pages: 0
                Product

                SciELO Brazil

                Categories
                Original Article

                Prevention,Transgender women,Syphilis,ISTs,Prevenção,Mulheres trans,Sífilis,Testing and treating,Point-of-care

                Comments

                Comment on this article