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      Androgen Receptor Splice Variant 7 Predicts Shorter Response in Patients with Metastatic Hormone-sensitive Prostate Cancer Receiving Androgen Deprivation Therapy.

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          Abstract

          Whether AR-V7 expression can predict the response in patients with metastatic hormone-sensitive prostate cancer (mHSPC) who receive androgen deprivation therapy (ADT) remains to be explored.

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          Author and article information

          Journal
          Eur Urol
          European urology
          Elsevier BV
          1873-7560
          0302-2838
          June 2021
          : 79
          : 6
          Affiliations
          [1 ] Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Institute of Urology of Hubei Province, Wuhan, China.
          [2 ] Department of Geriatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
          [3 ] Department of Urology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
          [4 ] Department of Urology, Chinese PLA General Hospital, Beijing, China.
          [5 ] Department of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
          [6 ] Department of Urology, the First Affiliated Hospital of Harbin Medical University, Harbin, China.
          [7 ] Department of Urology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
          [8 ] Department of Urology, the First Affiliated Hospital of Nanchang University, Nanchang, China.
          [9 ] Department of Pathology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
          [10 ] Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
          [11 ] Department of Pathology, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
          [12 ] Department of Pathology, the First Affiliated Hospital of Harbin Medical University, Harbin, China.
          [13 ] Department of Pathology, Chinese PLA General Hospital, Beijing, China.
          [14 ] Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Institute of Urology of Hubei Province, Wuhan, China. Electronic address: xuhuawhu@163.com.
          Article
          S0302-2838(21)00078-6
          10.1016/j.eururo.2021.01.037
          33579577
          66effce9-9f60-4034-8972-ca8f104011aa
          History

          Androgen deprivation therapy,Metastatic hormone-sensitive prostate cancer,Prospective cohort study,Androgen receptor splice variant 7,Immunohistochemical staining

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