Psychological disorders in patients with chronic constipation.

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Abstract

The aim of present study was to screen two categories of psychiatric disorders in chronic functional constipation.

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Most cited references 21

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The Hospital Anxiety and Depression Scale (HADS): translation and validation study of the Iranian version

Ali Montazeri, Mariam Vahdaninia, Mandana Ebrahimi … (2003)

Background The Hospital Anxiety and Depression Scale (HADS) is a widely used instrument to measure psychological morbidity in cancer patients. This study aimed to translate and test the reliability and validity of the Iranian version of the HADS. Methods The English language version of the HADS was translated into Persian (Iranian language) and was used in this study. The questionnaire was administered to a consecutive sample of 167 breast cancer patients and statistical analysis was performed to test the reliability and validity of the HADS. Results In general the Iranian version of the HADS was found to be acceptable to almost all patients (99%). Cronbach's alpha coefficient (to test reliability) has been found to be 0.78 for the HADS anxiety sub-scale and 0.86 for the HADS depression sub-scale. Validity as performed using known groups comparison analysis showed satisfactory results. Both anxiety and depression sub-scales discriminated well between sub-groups of patients differing in clinical status as defined by their disease stage. Conclusion This preliminary validation study of the Iranian version of the HADS proved that it is an acceptable, a reliable and valid measure of psychological distress among cancer patients.

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Central nervous system involvement in functional gastrointestinal disorders.

Jan Tack, Koen Demyttenaere, Lukas Oudenhove … (2004)

Although functional gastrointestinal disorders (FGID) are common, their pathophysiology remains incompletely understood. It is generally accepted that dysfunction of the bidirectional pathways between the gastrointestinal tract and the central nervous system (the 'brain-gut axis') at any level can cause FGID symptoms. In this review article, we focus on the role of the central nervous system in the brain-gut axis. First, we describe the functional anatomy of the brain-gut axis. Second, we focus on the results from brain-imaging studies both in healthy volunteers and in FGID patients. These new investigational techniques made identification of brain regions critically involved in processing of visceral afferent information possible. Differences in central nervous system response to visceral stimuli between controls and FGID patients will be highlighted. Third, we will address the issue of high comorbidity with psychiatric disorders. Some hypotheses about common pathophysiological substrates will be discussed.

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Irritable bowel syndrome, anxiety, and depression: what are the links?

R Lydiard (2000)

Irritable bowel syndrome (IBS) is a common and potentially disabling functional gastrointestinal disorder characterized by abdominal pain and altered bowel patterns. A significant amount of clinical and research data suggest the importance of the brain-gut interaction in IBS. This review examines the observed high prevalence of psychiatric disorders in patients with IBS. The published literature indicates that fewer than half of individuals with IBS seek treatment for it. Of those who do, 50% to 90% have psychiatric disorders, including panic disorder, generalized anxiety disorder, social phobia, posttraumatic stress disorder, and major depression, while those who do not seek treatment tend to be psychologically normal. Both physiologic and psychosocial variables appear to play important roles in the development and maintenance of IBS. Recent information suggests that the association of IBS and psychiatric disorders may be more fundamental than was previously believed. A brain-gut model for IBS is presented, and the role of traumatic stress and corticotropin-releasing factor as modulators of the brain-gut loop is discussed. Finally, the rationale for the use of psychotropic agents in the treatment of IBS with or without psychiatric symptoms is presented.

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Author and article information

Journal

Journal ID (iso-abbrev): Gastroenterol Hepatol Bed Bench

Title: Gastroenterology and hepatology from bed to bench

Publisher:

ISSN: 2008-2258

ISSN (Print): 2008-2258

Publication date (Electronic): 2011

Volume: 4

Issue: 3

Affiliations

[1 ] Health psychologist, University of Tehran, Tehran, Iran.

[2 ] Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Article

PMC ID: 4017427

PubMed ID: 24834176

SO-VID: 1a417649-98df-410a-b299-46cf4e538856

History

Keywords: Functional Gastrointestinal Disorder,psychiatric disorders,Rome III criteria

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Keywords: Functional Gastrointestinal Disorder, psychiatric disorders, Rome III criteria

Psychological disorders in patients with chronic constipation.

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Most cited references 21

The Hospital Anxiety and Depression Scale (HADS): translation and validation study of the Iranian version

Central nervous system involvement in functional gastrointestinal disorders.

Irritable bowel syndrome, anxiety, and depression: what are the links?

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