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      Potentially Inappropriate End of Life Care and Healthcare Costs in the Last 30 Days of Life in Regions Providing Integrated Palliative Care in the Netherlands: A Registration-based Study

      research-article
      1 , 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 3 , 1 , 2 , 3 , 16 , 1 , 16 , 1 , 2
      International Journal of Integrated Care
      Ubiquity Press
      palliative care, integrated palliative care, potentially inappropriate end of life care, healthcare costs, Medicine, Nursing, Health economics, Deceased adults

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          Abstract

          Introduction:

          This study aimed to assess the effect of integrated palliative care (IPC) on potentially inappropriate end- of-life care and healthcare-costs in the last 30 days of life in the Netherlands.

          Methods:

          Nationwide health-insurance claims data were used to assess potentially inappropriate end-of-life care (≥2 emergency room visits; ≥2 hospital admissions; >14 days hospitalization; chemotherapy; ICU admission; hospital death) and healthcare-costs in all deceased adults in IPC regions pre- and post- implementation and in those receiving IPC compared to a 1:2 matched control group.

          Results:

          In regions providing IPC deceased adults (n = 37,468) received significantly less potentially inappropriate end-of-life care post-implementation compared to pre-implementation (26.5% vs 27.9%; p < 0.05). Deceased adults who received IPC (n = 210) also received significantly less potentially inappropriate end-of-life care compared to a matched control group (14.8% vs 28.3%; p < 0.05). Mean hospital costs significantly decreased for deceased adults who received IPC (€2,817), while mean costs increased for general practitioner services (€311) and home care (€1,632).

          Discussion:

          These results highlight the importance of implementation of integrated palliative care and suitable payment. Further research in a larger sample is needed.

          Conclusion:

          This study shows less potentially inappropriate end-of-life care and a shift in healthcare costs from hospital to general practitioner and home care with IPC.

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          Most cited references45

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          Early palliative care for patients with metastatic non-small-cell lung cancer.

          Patients with metastatic non-small-cell lung cancer have a substantial symptom burden and may receive aggressive care at the end of life. We examined the effect of introducing palliative care early after diagnosis on patient-reported outcomes and end-of-life care among ambulatory patients with newly diagnosed disease. We randomly assigned patients with newly diagnosed metastatic non-small-cell lung cancer to receive either early palliative care integrated with standard oncologic care or standard oncologic care alone. Quality of life and mood were assessed at baseline and at 12 weeks with the use of the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale and the Hospital Anxiety and Depression Scale, respectively. The primary outcome was the change in the quality of life at 12 weeks. Data on end-of-life care were collected from electronic medical records. Of the 151 patients who underwent randomization, 27 died by 12 weeks and 107 (86% of the remaining patients) completed assessments. Patients assigned to early palliative care had a better quality of life than did patients assigned to standard care (mean score on the FACT-L scale [in which scores range from 0 to 136, with higher scores indicating better quality of life], 98.0 vs. 91.5; P=0.03). In addition, fewer patients in the palliative care group than in the standard care group had depressive symptoms (16% vs. 38%, P=0.01). Despite the fact that fewer patients in the early palliative care group than in the standard care group received aggressive end-of-life care (33% vs. 54%, P=0.05), median survival was longer among patients receiving early palliative care (11.6 months vs. 8.9 months, P=0.02). Among patients with metastatic non-small-cell lung cancer, early palliative care led to significant improvements in both quality of life and mood. As compared with patients receiving standard care, patients receiving early palliative care had less aggressive care at the end of life but longer survival. (Funded by an American Society of Clinical Oncology Career Development Award and philanthropic gifts; ClinicalTrials.gov number, NCT01038271.)
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            The escalating global burden of serious health-related suffering: projections to 2060 by world regions, age groups, and health conditions

            Summary Background Serious life-threatening and life-limiting illnesses place an enormous burden on society and health systems. Understanding how this burden will evolve in the future is essential to inform policies that alleviate suffering and prevent health system weakening. We aimed to project the global burden of serious health-related suffering requiring palliative care until 2060 by world regions, age groups, and health conditions. Methods We projected the future burden of serious health-related suffering as defined by the Lancet Commission on Palliative Care and Pain Relief, by combining WHO mortality projections (2016–60) with estimates of physical and psychological symptom prevalence in 20 conditions most often associated with symptoms requiring palliative care. Projections were described in terms of absolute numbers and proportional change compared with the 2016 baseline data. Results were stratified by World Bank income regions and WHO geographical regions. Findings By 2060, an estimated 48 million people (47% of all deaths globally) will die with serious health-related suffering, which represents an 87% increase from 26 million people in 2016. 83% of these deaths will occur in low-income and middle-income countries. Serious health-related suffering will increase in all regions, with the largest proportional rise in low-income countries (155% increase between 2016 and 2060). Globally, serious health-related suffering will increase most rapidly among people aged 70 years or older (183% increase between 2016 and 2060). In absolute terms, it will be driven by rises in cancer deaths (16 million people, 109% increase between 2016 and 2060). The condition with the highest proportional increase in serious-related suffering will be dementia (6 million people, 264% increase between 2016 and 2060). Interpretation The burden of serious health-related suffering will almost double by 2060, with the fastest increases occurring in low-income countries, among older people, and people with dementia. Immediate global action to integrate palliative care into health systems is an ethical and economic imperative. Funding Research Challenge Fund, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London.
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              Waste in the US Health Care System

              The United States spends more on health care than any other country, with costs approaching 18% of the gross domestic product (GDP). Prior studies estimated that approximately 30% of health care spending may be considered waste. Despite efforts to reduce overtreatment, improve care, and address overpayment, it is likely that substantial waste in US health care spending remains.
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                Author and article information

                Contributors
                Journal
                Int J Integr Care
                Int J Integr Care
                1568-4156
                International Journal of Integrated Care
                Ubiquity Press
                1568-4156
                08 July 2024
                Jul-Sep 2024
                : 24
                : 3
                : 6
                Affiliations
                [1 ]Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands
                [2 ]Netherlands Association for Palliative Care, Utrecht, The Netherlands
                [3 ]Center of Expertise in Palliative Care, Leiden University Medical Center, Leiden, The Netherlands
                [4 ]Gelre Hospitals, Apeldoorn, Netherlands Apeldoorn, The Netherlands
                [5 ]Synchroon, Oss, The Netherlands
                [6 ]Proscoop, Zwolle, The Netherlands
                [7 ]Center of Expertise in Palliative Care Utrecht, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands
                [8 ]Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam UMC –Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
                [9 ]Center of Expertise Urban Vitality, Faculty of Health, Amsterdam University of Applied Science, Amsterdam, the Netherlands
                [10 ]Department of Health Services Research, CAPHRI School for Public Health and Primary Care, Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
                [11 ]Zuyderland Care, Zuyderland Medical Center, Sittard-Geleen, The Netherlands
                [12 ]Department of Anaesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
                [13 ]Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
                [14 ]Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC –. Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
                [15 ]Center of Expertise in Palliative Care, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands
                [16 ]Radboud Institute for Health Sciences, Scientific Center for Quality of Healthcare (IQ healthcare), Radboud University Medical Center, Nijmegen, The Netherlands
                Author information
                https://orcid.org/0009-0007-5923-2331
                https://orcid.org/0000-0002-6310-9914
                https://orcid.org/0000-0003-3625-7839
                https://orcid.org/0000-0003-0959-9593
                https://orcid.org/0000-0002-5399-6513
                https://orcid.org/0000-0002-8880-2029
                https://orcid.org/0000-0001-5584-4305
                https://orcid.org/0000-0002-9440-1248
                https://orcid.org/0000-0002-2446-2862
                https://orcid.org/0000-0002-9003-6124
                https://orcid.org/0000-0003-2158-8221
                https://orcid.org/0000-0002-4198-2448
                https://orcid.org/0000-0002-0687-9760
                https://orcid.org/0000-0002-3000-2520
                Article
                10.5334/ijic.7504
                11243768
                39005964
                a4fe01ca-29f5-4dfa-80e7-09b24ceed17f
                Copyright: © 2024 The Author(s)

                This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.

                History
                : 04 November 2022
                : 19 June 2024
                Categories
                Research and Theory

                Health & Social care
                palliative care,integrated palliative care,potentially inappropriate end of life care,healthcare costs,medicine,nursing,health economics,deceased adults

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