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The long and short of microRNA.

Author(s): Luke Yates, Chris Norbury, Robert Gilbert

Publication date: 2013-04-25

Journal: Cell

Keywords: Animals, Gene Expression Regulation, Humans, MicroRNAs, chemistry, genetics, metabolism, RNA Processing, Post-Transcriptional, Ribonuclease III

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Abstract

MicroRNAs (miRNAs) are versatile regulators of gene expression in higher eukaryotes. In order to silence many different mRNAs in a precise manner, miRNA stability and efficacy is controlled by highly developed regulatory pathways and fine-tuning mechanisms both affecting miRNA processing and altering mature miRNA target specificity. Copyright © 2013 Elsevier Inc. All rights reserved.

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PubMed ID:: 23622238

DOI:: 10.1016/j.cell.2013.04.003

ScienceOpen disciplines: Chemistry

Keywords: Animals,Gene Expression Regulation,Humans,MicroRNAs,chemistry,genetics,metabolism,RNA Processing, Post-Transcriptional,Ribonuclease III

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ScienceOpen disciplines: Chemistry

Keywords: Animals, Gene Expression Regulation, Humans, MicroRNAs, chemistry, genetics, metabolism, RNA Processing, Post-Transcriptional, Ribonuclease III

The long and short of microRNA.

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