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      Acute pancreatitis.

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          Abstract

          Acute pancreatitis is an unpredictable and potentially lethal disease. The prognosis mainly depends on the development of organ failure and secondary infection of pancreatic or peripancreatic necrosis. In the past 10 years, treatment of acute pancreatitis has moved towards a multidisciplinary, tailored, and minimally invasive approach. Despite improvements in treatment and critical care, severe acute pancreatitis is still associated with high mortality rates. In this Seminar, we outline the latest evidence on diagnostic and therapeutic strategies for acute pancreatitis.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          September 05 2020
          : 396
          : 10252
          Affiliations
          [1 ] Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
          [2 ] Department of Surgery, Maastricht University Medical Center+, Maastricht, Netherlands.
          [3 ] Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands.
          [4 ] Department of Gastroenterology and Hepatology, St Antonius Hospital, Nieuwegein, Netherlands.
          [5 ] Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
          [6 ] Department of Surgery, St Antonius Hospital, Nieuwegein, Netherlands; Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands.
          [7 ] Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. Electronic address: m.g.besselink@amsterdamumc.nl.
          Article
          S0140-6736(20)31310-6
          10.1016/S0140-6736(20)31310-6
          32891214
          ab93a045-24c7-43b9-8f93-0842656f0b55
          Copyright © 2020 Elsevier Ltd. All rights reserved.
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