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      Platelet-rich Fibrin Improves the Osteo-/Odontogenic Differentiation of Stem Cells from Apical Papilla via the Extracellular Signal-regulated Protein Kinase Signaling Pathway.

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          Abstract

          The aim of this study was to investigate the cytobiological effects of platelet-rich fibrin (PRF) on stem cells from the apical papilla (SCAPs) in vitro and to further explore the underlying molecular mechanisms.

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          Author and article information

          Journal
          J Endod
          Journal of endodontics
          Elsevier BV
          1878-3554
          0099-2399
          May 2020
          : 46
          : 5
          Affiliations
          [1 ] Department of Pediatric Dentistry, School and Hospital of Stomatology, China Medical University, Shenyang, China; Deparrment of Oral Tissue Regeneration, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China.
          [2 ] Department of Pediatric Dentistry, School and Hospital of Stomatology, China Medical University, Shenyang, China; Deparrment of Oral Tissue Regeneration, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China. Electronic address: chenxu@cmu.edu.cn.
          Article
          S0099-2399(20)30085-6
          10.1016/j.joen.2020.02.004
          32201071
          ffecc5be-c931-4b3a-9df1-09fef6d137ca
          History

          Extracellular signal–regulated protein kinase signaling pathway,osteo-/odontogenic differentiation,platelet-rich fibrin,regenerative endodontic treatment,stem cells from the apical papilla

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