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      Heteroaromatization with 4-Hydroxycoumarin Part II: Synthesis of Some New Pyrano[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines and Pyrimido[1,6-b]-[1,2,4]triazine Derivatives.

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          Abstract

          A variety of novel [1,2,4]triazolo[1,5-c]pyrimidine-13-ones ( 4a- f) and ( 5b- d) could be obtained via reaction of 9-amino-7-(4’-chlorophenyl)-8,9-dihydro-8-imino-6 H,7H-[1]benzopyrano[3`,4`:5,6]pyrano[2,3-d]pyrimidine-6-one ( 3) with a variety of reagents. Pyrano[2,3-d]pyrimidine-6-ones 5a, 8a-c and pyrimido[1,6-b][1,2,4]-triazine-3,14-dione ( 6) were also prepared. The antimicrobial activity of some of the synthesized compounds was tested.

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          On the reaction of 2-aminopyridines withalpha-halocarbonyl compounds

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            Author and article information

            Journal
            Molecules
            Molecules
            molecules
            Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
            MDPI
            1420-3049
            31 May 2001
            June 2001
            : 6
            : 6
            : 519-527
            Affiliations
            [1 ]Department of Chemistry, Faculty of Science, Al- Azhar Univ. Nasr City, Cairo, Egypt. Fax: 002(02)2629356
            [2 ]Department of Chemistry, Faculty of Science, Al- Azhar Univ. (Girls), Nasr City, Cairo, Egypt.
            Author notes
            [* ]Author to whom correspondence should be addressed; E-mail: elagrody_am@ 123456yahoo.com
            Article
            molecules-06-00519
            10.3390/60600519
            6236442
            db46b2fc-fc13-46aa-92eb-fe2a9ae1cccf
            © 2001 by MDPI (http://www.mdpi.org).

            Reproduction is permitted for noncommercial purposes.

            History
            : 08 June 2000
            : 16 September 2000
            : 15 February 2001
            Categories
            Article

            pyrano[3,2-c][1]benzopyrans,pyrano[2,3-d]pyrimidines,[1,2,4]-triazolo-[1,5-c]pyrimidines,pyrimido[1,6-b][1,2,4]triazine,antimicrobial activities

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