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      Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection.

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          Abstract

          COVID-19 manifests with respiratory, systemic, and gastrointestinal (GI) symptoms.1, SARS-CoV-2 RNA is detected in respiratory and fecal samples, and recent reports demonstrate viral replication in both the lung and intestinal tissue.2, 3, 4 Although much is known about early fecal RNA shedding, little is known about long-term shedding, especially in those with mild COVID-19. Furthermore, most reports of fecal RNA shedding do not correlate these findings with GI symptoms.5.

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          Author and article information

          Journal
          Med (N Y)
          Med (New York, N.Y.)
          Elsevier BV
          2666-6340
          2666-6340
          Jun 10 2022
          : 3
          : 6
          Affiliations
          [1 ] Department of Genetics, Stanford University, 269 Campus Dr, CCSR 1155b, Stanford, CA, USA.
          [2 ] Department of Medicine (Hematology, Blood and Marrow Transplantation), Stanford University, Stanford, CA, USA.
          [3 ] Quantitative Science Unit, Stanford University, Stanford, CA, USA.
          [4 ] Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.
          [5 ] Department of Medicine (Infectious Diseases and Geographic Medicine), Stanford University, Stanford, CA, USA.
          [6 ] Department of Medicine (Infectious Diseases), Stanford University, Stanford, CA, USA.
          [7 ] Department of Medicine (Epidemiology and Population Health), Stanford University, Stanford, CA, USA.
          [8 ] Department of Pathology, Stanford University, Stanford, CA, USA.
          Article
          S2666-6340(22)00167-2
          10.1016/j.medj.2022.04.001
          9005383
          35434682
          1f2f6b53-ddeb-4819-abe8-f6bc222d05df
          History

          fecal RNA,viral shedding,gastrointestinal infection,SARS-CoV-2,COVID-19

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