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4,192
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Record
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Abstract
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A new modality for immunosuppression: targeting the JAK/STAT pathway.
Author(s):
Marko Pesu
,
John J. O’Shea
,
Paul Changelian
,
Dominic Borie
Publication date:
2004-06-30
Journal:
Nature reviews. Drug discovery
Keywords:
Animals
,
Enzyme Inhibitors
,
chemistry
,
pharmacology
,
Humans
,
Immunosuppression
,
methods
,
Immunosuppressive Agents
,
Interleukin Receptor Common gamma Subunit
,
Janus Kinase 3
,
Molecular Structure
,
Mutation
,
Protein-Tyrosine Kinases
,
antagonists & inhibitors
,
genetics
,
Receptors, Interleukin-7
,
immunology
,
Severe Combined Immunodeficiency
,
drug therapy
,
enzymology
,
Signal Transduction
,
drug effects
,
Trans-Activators
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There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
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Methods by AKJournals
Author and article information
Journal
PubMed ID::
15232577
DOI::
10.1038/nrd1441
ScienceOpen disciplines:
Chemistry
Keywords:
Animals
,
Enzyme Inhibitors
,
chemistry
,
pharmacology
,
Humans
,
Immunosuppression
,
methods
,
Immunosuppressive Agents
,
Interleukin Receptor Common gamma Subunit
,
Janus Kinase 3
,
Molecular Structure
,
Mutation
,
Protein-Tyrosine Kinases
,
antagonists & inhibitors
,
genetics
,
Receptors, Interleukin-7
,
immunology
,
Severe Combined Immunodeficiency
,
drug therapy
,
enzymology
,
Signal Transduction
,
drug effects
,
Trans-Activators
Data availability:
ScienceOpen disciplines:
Chemistry
Keywords:
Animals
,
Enzyme Inhibitors
,
chemistry
,
pharmacology
,
Humans
,
Immunosuppression
,
methods
,
Immunosuppressive Agents
,
Interleukin Receptor Common gamma Subunit
,
Janus Kinase 3
,
Molecular Structure
,
Mutation
,
Protein-Tyrosine Kinases
,
antagonists & inhibitors
,
genetics
,
Receptors, Interleukin-7
,
immunology
,
Severe Combined Immunodeficiency
,
drug therapy
,
enzymology
,
Signal Transduction
,
drug effects
,
Trans-Activators
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