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      Duration of untreated psychosis as predictor of long-term outcome in schizophrenia: systematic review and meta-analysis.

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          Abstract

          Duration of untreated psychosis (DUP) is one of the few potentially modifiable predictors of outcomes of schizophrenia. Long DUP as a predictor of poor short-term outcome has been addressed in previous meta-analyses, but the long-term effects of DUP remain unclear.

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          Most cited references46

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          Measuring inconsistency in meta-analyses.

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            A power primer.

            One possible reason for the continued neglect of statistical power analysis in research in the behavioral sciences is the inaccessibility of or difficulty with the standard material. A convenient, although not comprehensive, presentation of required sample sizes is provided here. Effect-size indexes and conventional values for these are given for operationally defined small, medium, and large effects. The sample sizes necessary for .80 power to detect effects at these levels are tabled for eight standard statistical tests: (a) the difference between independent means, (b) the significance of a product-moment correlation, (c) the difference between independent rs, (d) the sign test, (e) the difference between independent proportions, (f) chi-square tests for goodness of fit and contingency tables, (g) one-way analysis of variance, and (h) the significance of a multiple or multiple partial correlation.
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              Meta-analysis of Observational Studies in EpidemiologyA Proposal for Reporting

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                Author and article information

                Journal
                Br J Psychiatry
                The British journal of psychiatry : the journal of mental science
                1472-1465
                0007-1250
                Aug 2014
                : 205
                : 2
                Affiliations
                [1 ] Matti Penttilä, MD, PhD, University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, and Oulu University Hospital, Oulu; Erika Jääskeläinen, MD, PhD, University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, and Institute of Health Sciences, and Oulu University Hospital, and Medical Research Center Oulu; Noora Hirvonen, MSc, University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, and Faculty of Humanities, Information Studies, Oulu; Matti Isohanni, MD, PhD, University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, and Oulu University Hospital, Oulu; Jouko Miettunen, PhD, University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, and Institute of Health Sciences, and Oulu University Hospital, and Medical Research Center Oulu, Finland.
                Article
                205/2/88
                10.1192/bjp.bp.113.127753
                25252316
                a7219945-6869-48da-a1be-078146fcf0c7
                Royal College of Psychiatrists.
                History

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