Health-related quality of life in patients with β-thalassemia: Data from the phase 3 BELIEVE trial of luspatercept.

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Abstract

Patients with transfusion-dependent (TD) β-thalassemia require long-term red blood cell transfusions (RBCTs) that lead to iron overload, impacting health-related quality of life (HRQoL).

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Journal

Journal ID (iso-abbrev): Eur J Haematol

Title: European journal of haematology

Publisher: Wiley

ISSN (Electronic): 1600-0609

ISSN (Print): 0902-4441

Publication date (Electronic): Jul 2023

Volume: 111

Issue: 1

Affiliations

[1 ] Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

[2 ] Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

[3 ] Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.

[4 ] Department of Haematology, Whittington Health NHS Trust, London, UK.

[5 ] Centre of Excellence in Rare Haematological Diseases-Haemoglobinopathies, Laiko General Hospital, Athens, Greece.

[6 ] Siriraj Hospital, Mahidol University, Bangkok, Thailand.

[7 ] University College London Hospitals NHS Foundation Trust, London, UK.

[8 ] Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

[9 ] Imagine Institute, INSERM Unité 1163, University of Paris, Paris, France.

[10 ] St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

[11 ] Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.

[12 ] Bristol Myers Squibb, Princeton, New Jersey, USA.

[13 ] Evidera, Waltham, Massachusetts, USA.

[14 ] Acceleron Pharma Inc., a Subsidiary of Merck & Co., Inc., Rahway, New Jersey, USA.

[15 ] Grande Ospedale Metropolitano Bianchi Melacrino Morelli, Reggio Calabria, Italy.

Article

DOI: 10.1111/ejh.13975

PubMed ID: 37095595

SO-VID: 05b15328-99ab-4d23-8b6b-b6e7d804b258

History

Keywords: beta-thalassemia,iron overload,quality of life

Data availability:

Keywords: beta-thalassemia, iron overload, quality of life

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