The impact of COVID-19 pandemic in colorectal cancer screening, a systematic review.

Grumann Bernardon, Manuela; Boni, Tiffani; Lavratti, Igor; Nunes, Ianne; dos Santos, Alessandra Ceci; Alt, Luciano

doi:10.14293/S2199-1006.1.SOR-.PPFUA6C.v1

Author Summary

Summary

Introduction: COVID-19 pandemic brought a major impact on cancer screening services, among those, colorectal cancer (CRC). This study evaluated the COVID-19 pandemic impact on the quantity of colonoscopies performed at different countries and its consequences.

Method: Articles from PUB-MED, Scielo and LILACS databases were manually collectedbetween April 25th and June 30th of 2021. Cross-sectional, observational and retrospective studies were selected; 11 articles remained applying the inclusion and exclusion criteria.

Results: There was significant reduction of colonoscopies performed during the COVID-19 pandemic demonstrated in all of the studies. A 90% reduction was shown in 3 studies, the lesser reduction was demonstrated by Challine et al., (2021), which was 20%. Also was found a reduction on CRC diagnosis during that period, 72% and 22% at UK in Rutter et al. (2021) and Morris et al., (2021), respectively. At Italy the reduction was of 11,9% as Buscarini et al., (2021) shows. Lui et al., (2020) demonstrated a 37% reduction at Hong-Kong.

Conclusion: The impact of COVID-19 pandemic in CRC screening and diagnostic services was significant, increasing the morbidity and mortality due to late diagnosis. Beyond that it was observed an increase on the diagnosis probability of colonoscopy during that period. More studies are required to fully understand the impact of the screening decreased capacity.

Abstract

Introduction: COVID-19 pandemic brought a major impact on cancer screening services, among those, colorectal cancer (CRC). This study evaluated the COVID-19 pandemic impact on the quantity of colonoscopies performed at different countries and its consequences.

Method: Articles from PUB-MED, Scielo and LILACS databases were manually collectedbetween April 25th and June 30th of 2021. Cross-sectional, observational and retrospective studies were selected; 11 articles remained applying the inclusion and exclusion criteria.

Results: There was significant reduction of colonoscopies performed during the COVID-19 pandemic demonstrated in all of the studies. A 90% reduction was shown in 3 studies, the lesser reduction was demonstrated by Challine et al., (2021), which was 20%. Also was found a reduction on CRC diagnosis during that period, 72% and 22% at UK in Rutter et al. (2021) and Morris et al., (2021), respectively. At Italy the reduction was of 11,9% as Buscarini et al., (2021) shows. Lui et al., (2020) demonstrated a 37% reduction at Hong-Kong.

Conclusion: The impact of COVID-19 pandemic in CRC screening and diagnostic services was significant, increasing the morbidity and mortality due to late diagnosis. Beyond that it was observed an increase on the diagnosis probability of colonoscopy during that period. More studies are required to fully understand the impact of the screening decreased capacity.

Content

Author and article information

Journal

Title: ScienceOpen Preprints

Publisher: ScienceOpen

Publication date (Electronic preprint): 4 September 2022

Affiliations

[1 ] Universidade de Passo Fundo

Author notes

[* ]Email: manuelabernardon79@ 123456gmail.com .

Author information

Manuela Bernardon https://orcid.org/0000-0003-4825-7852

Article

DOI: 10.14293/S2199-1006.1.SOR-.PPFUA6C.v1

SO-VID: 6fd1a34c-a6ba-4771-a7e9-de42856a8661

License:

This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

History

Date received : 4 September 2022

Data availability: All data generated or analysed during this study are included in this published article (and its supplementary information files).

ScienceOpen disciplines: Medicine

Keywords: Colonoscopy,Cancer,Diagnosis,COVID- 19

References

Kadakuntla Anusri, Wang Tiffany, Medgyesy Karen, Rrapi Enxhi, Litynski James, Adynski Gillian, Tadros Micheal. Colorectal cancer screening in the COVID-19 era. World Journal of Gastrointestinal Oncology. Vol. 13(4):238–251. 2021. Baishideng Publishing Group Inc. [Cross Ref]
Gashti Sarah Menezes, Tondo André Luiz Caramori, Freitag Isabella, De Araújo Juliana Maria Mendes, Rochemback Liliane, Orth Luiza, Lira Marina, Rezende Paula Donizete, Gomes Silvia Campos, Pareja Helen Brambila Jorge. Câncer colorretal: principais complicações e a importância do diagnóstico precoce. Revista Eletrônica Acervo Saúde. Vol. 13(4)2021. Revista Eletronica Acervo Saude. [Cross Ref]
Lima Jéssica Ferreira de, Macedo Aline Barbosa, Panizzon Cynthia Priscilla do N. Bonato, Perles Juliana Vanessa Colombo Martins. CÂNCER COLORRETAL, DIAGNÓSTICO E ESTADIAMENTO: REVISÃO DE LITERATURA. Arquivos do Mudi. Vol. 23(3):315–329. 2019. Universidade Estadual de Maringa. [Cross Ref]
Dubé Catherine. Re-FIT-ting Colorectal Cancer Screening During and Beyond COVID. Gastroenterology. Vol. 161(2):418–420. 2021. Elsevier BV. [Cross Ref]
Rutter Matthew D, Brookes Matthew, Lee Thomas J, Rogers Peter, Sharp Linda. Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: a National Endoscopy Database Analysis. Gut. Vol. 70(3):537–543. 2021. BMJ. [Cross Ref]
Malta Deborah Carvalho, Gomes Crizian Saar, Silva Alanna Gomes da, Cardoso Laís Santos de Magalhães, Barros Marilisa Berti de Azevedo, Lima Margareth Guimarães, Souza Junior Paulo Roberto Borges de, Szwarcwald Célia Landmann. Uso dos serviços de saúde e adesão ao distanciamento social por adultos com doenças crônicas na pandemia de COVID-19, Brasil, 2020. Ciência & Saúde Coletiva. Vol. 26(7):2833–2842. 2021. FapUNIFESP (SciELO). [Cross Ref]
Almeida André Luiz Cerqueira, Santo Thyago Monteiro do Espírito, Mello Maurício Silva Santana, Cedro Alexandre Viana, Lopes Nilson Lima, Ribeiro Ana Paloma Martins Rocha, Mota João Gustavo Cerqueira, Mendes Rodrigo Serapião, Almeida Paulo André Abreu, Ferreira Murilo Araújo, Arruda Diego Moreira, Santos Adriana Aguiar Pepe, Rios Vinícius Guedes, Dantas Maria Rosa Nascimento, Silva Viviane Almeida, Silva Marcos Gomes da, Sampaio Patrick Harrison Santana, Guimarães André Raimundo, Santos Edval Gomes. Repercussões da Pandemia de COVID-19 na Prática Assistencial de um Hospital Terciário. Arquivos Brasileiros de Cardiologia. 2020. Sociedade Brasileira de Cardiologia. [Cross Ref]
Morris Eva J A, Goldacre Raphael, Spata Enti, Mafham Marion, Finan Paul J, Shelton Jon, Richards Mike, Spencer Katie, Emberson Jonathan, Hollings Sam, Curnow Paula, Gair Dominic, Sebag-Montefiore David, Cunningham Chris, Rutter Matthew D, Nicholson Brian D, Rashbass Jem, Landray Martin, Collins Rory, Casadei Barbara, Baigent Colin. Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study. The Lancet Gastroenterology & Hepatology. Vol. 6(3):199–208. 2021. Elsevier BV. [Cross Ref]
Lantinga Marten A., Theunissen Felix, ter Borg Pieter C. J., Bruno Marco J., Ouwendijk Rob J. T., Siersema Peter D.. Impact of the COVID-19 pandemic on gastrointestinal endoscopy in the Netherlands: analysis of a prospective endoscopy database. Endoscopy. Vol. 53(02):166–170. 2021. Georg Thieme Verlag KG. [Cross Ref]
Lui Thomas K.L., Leung Kathy, Guo Chuan-Guo, Tsui Vivien W.M., Wu Joseph T., Leung Wai K.. Impacts of the Coronavirus 2019 Pandemic on Gastrointestinal Endoscopy Volume and Diagnosis of Gastric and Colorectal Cancers: A Population-Based Study. Gastroenterology. Vol. 159(3)2020. Elsevier BV. [Cross Ref]
Patel Shreya, Issaka Rachel B., Chen Ellen, Somsouk Ma. Colorectal Cancer Screening and COVID-19. American Journal of Gastroenterology. Vol. 116(2):433–434. 2021. Ovid Technologies (Wolters Kluwer Health). [Cross Ref]
Challine Alexandre, Lazzati Andrea, Dousset Bertrand, Voron Thibault, Parc Yann, Lefevre Jeremie H.. Colorectal screening: We have not caught up. A surge of colorectal cancer after the coronavirus disease 2019 (COVID-19) pandemic? Surgery. Vol. 169(4):991–993. 2021. Elsevier BV. [Cross Ref]
Meyer Antoine, Drouin Jérôme, Zureik Mahmoud, Weill Alain, Dray-Spira Rosemary. Colonoscopy in France during the COVID-19 pandemic. International Journal of Colorectal Disease. Vol. 36(5):1073–1075. 2021. Springer Science and Business Media LLC. [Cross Ref]
Raj Kumar Barath, Pandey Diwakar, Rohila Jitender, deSouza Ashwin, Saklani Avanish. An observational study of the demographic and treatment changes in a tertiary colorectal cancer center during the COVID‐19 pandemic. Journal of Surgical Oncology. Vol. 122(7):1271–1275. 2020. Wiley. [Cross Ref]
Gorin Sherri N. Sheinfeld, Jimbo Masahito, Heizelman Robert, Harmes Kathryn M., Harper Diane M.. The future of cancer screening after COVID‐19 may be at home. Cancer. Vol. 127(4):498–503. 2021. Wiley. [Cross Ref]
Buscarini Elisabetta, Benedetti Antonio, Monica Fabio, Pasquale Luigi, Buttitta Francesco, Cameletti Michela, Ferrari Clarissa, Ricciardiello Luigi, Massironi Sara, Bianco Maria Antonia, Germanà Bastianello, Rodinò Stefano, Anderloni Andrea, Mussetto Alessandro, Nipote Bruno, Russo Salvatore, Manta Raffaele, Lauri Adriano, Occhipinti Vincenzo, Marco Marco Di, Giovannone Maurizio, Binda Cecilia, Sbrancia Monica, Paolo Maria Carla Di, de’-Angelis Gian Luigi, Fiori Giancarla, Dal-Fante Marco, Caro Giuseppe de, Usai-Satta Paolo, Cesarini Monica, Piras Enrico, Stasi Elisa, Serio Giovanni, Montalbano Luigi Maria, Mirante Vincenzo Giorgio, Burattini Osvaldo, Attardo Simona, Bargiggia Stefano, Dinca Manuele, Missale Guido, Alvisi Costanza, Broglia Francesco, Ferraris Luca, Conti-Bellocchi Maria Cristina, Luigiano Carmelo, Pallio Socrate, Brunacci Matteo, Manfrini Carlo, Bozzi Rosamaria, Checchin Davide, Togliani Thomas, D'errico Antonietta, Bazzoli Franco, La Bianca Orazio, Berretti Debora, Alvaro Domenico. Changes in digestive cancer diagnosis during the SARS-CoV-2 pandemic in Italy: A nationwide survey. Digestive and Liver Disease. Vol. 53(6):682–688. 2021. Elsevier BV. [Cross Ref]
Adhikari Sasmita Poudel, Meng Sha, Wu Yu-Ju, Mao Yu-Ping, Ye Rui-Xue, Wang Qing-Zhi, Sun Chang, Sylvia Sean, Rozelle Scott, Raat Hein, Zhou Huan. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. Infectious Diseases of Poverty. Vol. 9(1)2020. Springer Science and Business Media LLC. [Cross Ref]
Gonçalves Ferreira Netto Raimundo, Do Nascimento Corrêa José Wilson. EPIDEMIOLOGIA DO SURTO DE DOENÇA POR CORONAVÍRUS (COVID-19). DESAFIOS - Revista Interdisciplinar da Universidade Federal do Tocantins. Vol. 7(Especial-3):18–25. 2020. Universidade Federal do Tocantins. [Cross Ref]

Comments

[1] Kadakuntla Anusri, Wang Tiffany, Medgyesy Karen, Rrapi Enxhi, Litynski James, Adynski Gillian, Tadros Micheal. Colorectal cancer screening in the COVID-19 era. World Journal of Gastrointestinal Oncology. Vol. 13(4):238–251. 2021. Baishideng Publishing Group Inc. [Cross Ref]

[2] Gashti Sarah Menezes, Tondo André Luiz Caramori, Freitag Isabella, De Araújo Juliana Maria Mendes, Rochemback Liliane, Orth Luiza, Lira Marina, Rezende Paula Donizete, Gomes Silvia Campos, Pareja Helen Brambila Jorge. Câncer colorretal: principais complicações e a importância do diagnóstico precoce. Revista Eletrônica Acervo Saúde. Vol. 13(4)2021. Revista Eletronica Acervo Saude. [Cross Ref]

[3] Lima Jéssica Ferreira de, Macedo Aline Barbosa, Panizzon Cynthia Priscilla do N. Bonato, Perles Juliana Vanessa Colombo Martins. CÂNCER COLORRETAL, DIAGNÓSTICO E ESTADIAMENTO: REVISÃO DE LITERATURA. Arquivos do Mudi. Vol. 23(3):315–329. 2019. Universidade Estadual de Maringa. [Cross Ref]

[4] Dubé Catherine. Re-FIT-ting Colorectal Cancer Screening During and Beyond COVID. Gastroenterology. Vol. 161(2):418–420. 2021. Elsevier BV. [Cross Ref]

[5] Rutter Matthew D, Brookes Matthew, Lee Thomas J, Rogers Peter, Sharp Linda. Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: a National Endoscopy Database Analysis. Gut. Vol. 70(3):537–543. 2021. BMJ. [Cross Ref]

[6] Malta Deborah Carvalho, Gomes Crizian Saar, Silva Alanna Gomes da, Cardoso Laís Santos de Magalhães, Barros Marilisa Berti de Azevedo, Lima Margareth Guimarães, Souza Junior Paulo Roberto Borges de, Szwarcwald Célia Landmann. Uso dos serviços de saúde e adesão ao distanciamento social por adultos com doenças crônicas na pandemia de COVID-19, Brasil, 2020. Ciência & Saúde Coletiva. Vol. 26(7):2833–2842. 2021. FapUNIFESP (SciELO). [Cross Ref]

[7] Almeida André Luiz Cerqueira, Santo Thyago Monteiro do Espírito, Mello Maurício Silva Santana, Cedro Alexandre Viana, Lopes Nilson Lima, Ribeiro Ana Paloma Martins Rocha, Mota João Gustavo Cerqueira, Mendes Rodrigo Serapião, Almeida Paulo André Abreu, Ferreira Murilo Araújo, Arruda Diego Moreira, Santos Adriana Aguiar Pepe, Rios Vinícius Guedes, Dantas Maria Rosa Nascimento, Silva Viviane Almeida, Silva Marcos Gomes da, Sampaio Patrick Harrison Santana, Guimarães André Raimundo, Santos Edval Gomes. Repercussões da Pandemia de COVID-19 na Prática Assistencial de um Hospital Terciário. Arquivos Brasileiros de Cardiologia. 2020. Sociedade Brasileira de Cardiologia. [Cross Ref]

[8] Morris Eva J A, Goldacre Raphael, Spata Enti, Mafham Marion, Finan Paul J, Shelton Jon, Richards Mike, Spencer Katie, Emberson Jonathan, Hollings Sam, Curnow Paula, Gair Dominic, Sebag-Montefiore David, Cunningham Chris, Rutter Matthew D, Nicholson Brian D, Rashbass Jem, Landray Martin, Collins Rory, Casadei Barbara, Baigent Colin. Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study. The Lancet Gastroenterology & Hepatology. Vol. 6(3):199–208. 2021. Elsevier BV. [Cross Ref]

[9] Lantinga Marten A., Theunissen Felix, ter Borg Pieter C. J., Bruno Marco J., Ouwendijk Rob J. T., Siersema Peter D.. Impact of the COVID-19 pandemic on gastrointestinal endoscopy in the Netherlands: analysis of a prospective endoscopy database. Endoscopy. Vol. 53(02):166–170. 2021. Georg Thieme Verlag KG. [Cross Ref]

[10] Lui Thomas K.L., Leung Kathy, Guo Chuan-Guo, Tsui Vivien W.M., Wu Joseph T., Leung Wai K.. Impacts of the Coronavirus 2019 Pandemic on Gastrointestinal Endoscopy Volume and Diagnosis of Gastric and Colorectal Cancers: A Population-Based Study. Gastroenterology. Vol. 159(3)2020. Elsevier BV. [Cross Ref]

[11] Patel Shreya, Issaka Rachel B., Chen Ellen, Somsouk Ma. Colorectal Cancer Screening and COVID-19. American Journal of Gastroenterology. Vol. 116(2):433–434. 2021. Ovid Technologies (Wolters Kluwer Health). [Cross Ref]

[12] Challine Alexandre, Lazzati Andrea, Dousset Bertrand, Voron Thibault, Parc Yann, Lefevre Jeremie H.. Colorectal screening: We have not caught up. A surge of colorectal cancer after the coronavirus disease 2019 (COVID-19) pandemic? Surgery. Vol. 169(4):991–993. 2021. Elsevier BV. [Cross Ref]

[13] Meyer Antoine, Drouin Jérôme, Zureik Mahmoud, Weill Alain, Dray-Spira Rosemary. Colonoscopy in France during the COVID-19 pandemic. International Journal of Colorectal Disease. Vol. 36(5):1073–1075. 2021. Springer Science and Business Media LLC. [Cross Ref]

[14] Raj Kumar Barath, Pandey Diwakar, Rohila Jitender, deSouza Ashwin, Saklani Avanish. An observational study of the demographic and treatment changes in a tertiary colorectal cancer center during the COVID‐19 pandemic. Journal of Surgical Oncology. Vol. 122(7):1271–1275. 2020. Wiley. [Cross Ref]

[15] Gorin Sherri N. Sheinfeld, Jimbo Masahito, Heizelman Robert, Harmes Kathryn M., Harper Diane M.. The future of cancer screening after COVID‐19 may be at home. Cancer. Vol. 127(4):498–503. 2021. Wiley. [Cross Ref]

[16] Buscarini Elisabetta, Benedetti Antonio, Monica Fabio, Pasquale Luigi, Buttitta Francesco, Cameletti Michela, Ferrari Clarissa, Ricciardiello Luigi, Massironi Sara, Bianco Maria Antonia, Germanà Bastianello, Rodinò Stefano, Anderloni Andrea, Mussetto Alessandro, Nipote Bruno, Russo Salvatore, Manta Raffaele, Lauri Adriano, Occhipinti Vincenzo, Marco Marco Di, Giovannone Maurizio, Binda Cecilia, Sbrancia Monica, Paolo Maria Carla Di, de’-Angelis Gian Luigi, Fiori Giancarla, Dal-Fante Marco, Caro Giuseppe de, Usai-Satta Paolo, Cesarini Monica, Piras Enrico, Stasi Elisa, Serio Giovanni, Montalbano Luigi Maria, Mirante Vincenzo Giorgio, Burattini Osvaldo, Attardo Simona, Bargiggia Stefano, Dinca Manuele, Missale Guido, Alvisi Costanza, Broglia Francesco, Ferraris Luca, Conti-Bellocchi Maria Cristina, Luigiano Carmelo, Pallio Socrate, Brunacci Matteo, Manfrini Carlo, Bozzi Rosamaria, Checchin Davide, Togliani Thomas, D'errico Antonietta, Bazzoli Franco, La Bianca Orazio, Berretti Debora, Alvaro Domenico. Changes in digestive cancer diagnosis during the SARS-CoV-2 pandemic in Italy: A nationwide survey. Digestive and Liver Disease. Vol. 53(6):682–688. 2021. Elsevier BV. [Cross Ref]

[17] Adhikari Sasmita Poudel, Meng Sha, Wu Yu-Ju, Mao Yu-Ping, Ye Rui-Xue, Wang Qing-Zhi, Sun Chang, Sylvia Sean, Rozelle Scott, Raat Hein, Zhou Huan. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. Infectious Diseases of Poverty. Vol. 9(1)2020. Springer Science and Business Media LLC. [Cross Ref]

[18] Gonçalves Ferreira Netto Raimundo, Do Nascimento Corrêa José Wilson. EPIDEMIOLOGIA DO SURTO DE DOENÇA POR CORONAVÍRUS (COVID-19). DESAFIOS - Revista Interdisciplinar da Universidade Federal do Tocantins. Vol. 7(Especial-3):18–25. 2020. Universidade Federal do Tocantins. [Cross Ref]