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      Preoperative prediction of microvascular invasion in hepatocellular cancer: a radiomics model using Gd-EOB-DTPA-enhanced MRI.

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          Abstract

          Preoperative prediction of microvascular invasion (MVI) in patients with hepatocellular cancer (HCC) is important for surgery strategy making. We aimed to develop and validate a combined intratumoural and peritumoural radiomics model based on gadolinium-ethoxybenzyl-diethylenetriamine (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) for preoperative prediction of MVI in primary HCC patients.

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          Author and article information

          Journal
          Eur Radiol
          European radiology
          Springer Science and Business Media LLC
          1432-1084
          0938-7994
          Sep 2019
          : 29
          : 9
          Affiliations
          [1 ] Department of Radiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
          [2 ] Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
          [3 ] National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China.
          [4 ] Clinical Trials Unit, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
          [5 ] GE Healthcare, Shanghai, China.
          [6 ] Department of Medical Ultrasonics, Division of Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
          [7 ] Department of Radiation Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
          [8 ] Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
          [9 ] Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, 58 Zhong Shan Road 2, Guangzhou, 510080, China.
          [10 ] Jinan University, Guangzhou, China.
          [11 ] Department of Oncology, The First Affiliated Hospital of Sun Yat-sen University, 58 Zhong Shan Road 2, Guangzhou, 510080, China. pzhenw@mail.sysu.edu.cn.
          [12 ] Department of Medical Ultrasonics, Division of Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. kuangminda@hotmail.com.
          [13 ] Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, 58 Zhong Shan Road 2, Guangzhou, 510080, China. kuangminda@hotmail.com.
          Article
          10.1007/s00330-018-5935-8
          10.1007/s00330-018-5935-8
          30689032
          ffa7c286-c6d6-4175-85bb-7d0d3524fed8
          History

          Gd-EOB-DTPA,Hepatocellular cancer,Magnetic resonance imaging,Radiomics

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