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A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer.
Torsten O Nielsen
1 ,
Joel S Parker ,
Samuel Leung ,
David Voduc ,
Mark Ebbert ,
Tammi Vickery ,
Sherri R Davies ,
Jacqueline Snider ,
Inge J Stijleman ,
Jerry Reed ,
Maggie C U Cheang ,
Elaine R Mardis ,
Charles M Perou ,
Philip S Bernard ,
Matthew J Ellis
Nov 01 2010
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Abstract
To compare clinical, immunohistochemical (IHC), and gene expression models of prognosis applicable to formalin-fixed, paraffin-embedded blocks in a large series of estrogen receptor (ER)-positive breast cancers from patients uniformly treated with adjuvant tamoxifen.