Association between plasma lipoprotein levels and bioprosthetic valve structural degeneration.

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Abstract

Structural valve degeneration (SVD) leads to the failure of aortic valve bioprostheses. It is suspected that lipid-derived factors could play a role in SVD. We hypothesised that oxidised low-density lipoprotein (OxLDL), OxLDL/LDL, OxLDL/high-density lipoprotein (OxLDL/HDL) and proprotein convertase subtilisin/kexin 9 (PCSK9) may be associated with SVD.

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Journal

Journal ID (iso-abbrev): Heart

Title: Heart (British Cardiac Society)

Publisher: BMJ

ISSN (Electronic): 1468-201X

ISSN (Print): 1355-6037

Publication date (Electronic): December 01 2016

Volume: 102

Issue: 23

Affiliations

[1 ] Laboratory of Cardiovascular Pathobiology, Department of Surgery, Quebec Heart and Lung Institute/Research Center, Laval University, Quebec, Quebec, Canada.

[2 ] Department of Medicine, Laval University, Québec, Quebec, Canada.

[3 ] Department of Kinesiology, Laval University, Québec, Quebec, Canada.

[4 ] Department of Molecular Medicine, Laval University, Québec, Quebec, Canada.

Article

Publisher Item ID: heartjnl-2016-309541

DOI: 10.1136/heartjnl-2016-309541

PubMed ID: 27378363

SO-VID: fd0f8aee-3382-4c15-8bd8-54429c647040

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