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      Association of Motoric Cognitive Risk Syndrome With Brain Volumes: Results From the GAIT Study.

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          Abstract

          The "motoric cognitive risk" (MCR) syndrome is a newly reported predementia syndrome combining cognitive complaint and slow gait speed. We hypothesized that individuals with MCR syndrome would have lower brain volumes compared with non-MCR individuals. This study aims (i) to compare the cognitive profile of nondemented older community-dwellers with and without MCR syndrome and (ii) to examine association of global and regional brain volumes with MCR syndrome.

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          Author and article information

          Journal
          J. Gerontol. A Biol. Sci. Med. Sci.
          The journals of gerontology. Series A, Biological sciences and medical sciences
          Oxford University Press (OUP)
          1758-535X
          1079-5006
          Aug 2016
          : 71
          : 8
          Affiliations
          [1 ] Department of Medicine, Division of Geriatric Medicine, Sir Mortimer B. Davis - Jewish General Hospital and Lady Davis Institute for Medical Research and Dr. Joseph Kaufmann Chair in Geriatric Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada. Centre of Excellence on Aging and Chronic Diseases of McGill integrated University Health Network, Montreal, Quebec, Canada. olivier.beauchet@mcgill.ca.
          [2 ] Department of Neurology, Geneva University Hospital and University of Geneva, Switzerland. Department of Neurology, Division of Cognitive & Motor Aging, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York.
          [3 ] Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital; University Memory Clinic of Angers; UPRES EA 4638, University of Angers, UNAM, Angers, France. Center for Functional and Metabolic Mapping, Robarts Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, Canada.
          [4 ] Department of Neurology, Division of Cognitive & Motor Aging, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York.
          Article
          glw012
          10.1093/gerona/glw012
          26946101
          fb95a757-e896-4c99-ad85-e15fc6e94942
          History

          Cognitive disorders,Gait disorders,Motor control,MRI
          Cognitive disorders, Gait disorders, Motor control, MRI

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