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      Triagem auditiva neonatal em recém-nascidos de mães soropositivas para o HIV Translated title: Newborn hearing screening in infants born to HIV-seropositive mothers

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          Abstract

          OBJETIVO: Analisar as emissões otoacústicas de crianças nascidas de mães soropositivas para o HIV na triagem auditiva neonatal. MÉTODOS: Realizou-se a pesquisa das Emissões Otoacústicas Evocadas por Transiente (EOAT) e do reflexo cócleo-palpebral (RCP) em 247 neonatos, todos nascidos a termo e sem fatores de risco para a audição. O Grupo Controle (GC) foi composto por 167 neonatos e o Grupo Pesquisa (GP) por 80 neonatos expostos ao HIV durante a gestação. Considerou-se "falha" quando o neonato apresentava ausência de EOAT em pelo menos uma das orelhas. Os dados foram analisados estatisticamente. RESULTADOS: No Grupo Pesquisa, oito (10%) neonatos falharam na triagem auditiva neonatal e no Grupo Controle este número foi de sete (4,2%) (p=0,09). No reteste dos neonatos que falharam, houve a persistência da ausência das emissões otoacústicas em um neonato do Grupo Pesquisa (12,5%) e em dois neonatos (28,6%) do Grupo Controle (p=0,6). Em todos os neonatos houve a presença do RCP. CONCLUSÃO: Não houve associação entre ausência de EOA por transiente e a exposição do neonato ao HIV durante a gestação.

          Translated abstract

          PURPOSE: To analyze the otoacoustic emissions (OAE) of the newborn hearing screening of infants born to HIV-seropositive mothers. METHODS: It was carried out the Transient-Evoked OAE and the research of cochleopalpebral reflex in 247 full-term newborns with no risk factors for hearing. The Control Group (CG) comprised 167 infants, and the Research Group (RG), 80 infants that had been exposed to HIV during gestation. It was considered "failure" when the newborn had absence of TOAE in at least one ear. Data were statistically analyzed. RESULTS: In the, Eight infants (10%) from the Research Group and seven (4.2%) from the Control Group failed in the newborn hearing screening (p=0.09). Retest of the infants who failed showed persistence of the absence of OAE in one subject (12.5%) from the Research Group and two (28.6%) from the Control Group (p=0.6). Cochleopalpebral reflex was present in all subjects. CONCLUSION: There was no association between the absence of TOAE and the newborn's HIV exposure during gestation.

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          Most cited references53

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          Year 2007 position statement: Principles and guidelines for early hearing detection and intervention programs.

          (2007)
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            Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)

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              Cationic N-confused porphyrin derivative as a better molecule scaffold for G-quadruplex recognition.

              One N-confused porphyrin derivative was prepared and its first observation that it could stabilize G-quadruplex and possessed high selectivity over duplex DNA was made, furthermore, it was also proved to possess the capacity to induce a structural transition from the antiparallel to the mixed-type hybrid G-quadruplex structure. Copyright (c) 2010 Elsevier Ltd. All rights reserved.
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                Author and article information

                Journal
                jsbf
                Jornal da Sociedade Brasileira de Fonoaudiologia
                J. Soc. Bras. Fonoaudiol.
                Sociedade Brasileira de Fonoaudiologia (São Paulo, SP, Brazil )
                2179-6491
                December 2011
                : 23
                : 4
                : 376-380
                Affiliations
                [01] Ribeirão Preto SP orgnameUniversidade de São Paulo orgdiv1Faculdade de Medicina de Ribeirão Preto orgdiv2Departamento de Otorrinolaringologia, Oftalmologia e Cirurgia de Cabeça e Pescoço Brasil
                [03] Ribeirão Preto SP orgnameUniversidade de São Paulo orgdiv1Hospital das Clínicas de Ribeirão Preto orgdiv2Centro de Reabilitação Brasil
                [02] Ribeirão Preto SP orgnameUniversidade de São Paulo orgdiv1Faculdade de Medicina de Ribeirão Preto orgdiv2Departamento de Otorrinolaringologia, Oftalmologia e Cirurgia de Cabeça e Pescoço Brasil
                Article
                S2179-64912011000400014 S2179-6491(11)02300414
                10.1590/S2179-64912011000400014
                fb8fc1fb-5c7f-4f4b-a24d-15cd53750096

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 24 August 2011
                : 27 March 2011
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 30, Pages: 5
                Product

                SciELO Brazil

                Categories
                Artigos Originais

                Infecções por HIV,Ear, inner,Neonatal screening,HIV seropositivity,Orelha interna,Hearing disorders,HIV infections,Hearing,Transtornos da audição,Audição,Triagem neonatal,Soropositividade para HIV

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