This is the updated supplementary information to accompany "Quantum supremacy using a programmable superconducting processor", an article published in the October 24, 2019 issue of Nature. The main article is freely available at https://www.nature.com/articles/s41586-019-1666-5 Summary of changes relative to the supplementary information dated October 8, 2019: Ref [49] is now published; Correction of notation and definition for variational distance in Sec XI B. Correction of corresponding equation in footnote (Ref [101]); Down-sampling of images in Figs. S1 and S4 to comply with arXiv storage limit; Miscellaneous typographical corrections; Clarification in Fig. S8 caption; URL for experimental data repository added to Ref [54], https://doi.org/10.5061/dryad.k6t1rj8