Wrist-based accelerometers are increasingly used to assess physical activity (PA) in population-based studies; however, cut-points to translate wrist-based accelerometer counts into PA intensity categories are still needed. The purpose of this study was to determine wrist-based cut-points for moderate and vigorous intensity ambulatory PA in adults for the Actical accelerometer. Healthy adults (n=24) completed a four-phase treadmill exercise protocol (1.9, 3.0, 4.0, and 5.2 mph) while wearing an Actical accelerometer on their wrist. MET levels were assessed by indirect calorimetry. Receiver operating characteristics (ROC) curves were generated to determine accelerometer counts that maximized sensitivity and specificity for classification of moderate (≥3 METs) and vigorous (>6 METs) ambulatory activity. The area under the ROC curves to discriminate moderate and vigorous intensity ambulatory activity were 0.93 (95% CI: 0.90–0.97; p <0.001) and 0.96 (95% CI: 0.94–0.99; p<0.001), respectively. The identified cut-point for moderate intensity ambulatory activity was 1031 counts/minute, which had a corresponding sensitivity and specificity of 85.6% and 87.5%, respectively. The identified cut-point for vigorous intensity ambulatory activity was 3589 counts/minute, which had a corresponding sensitivity and specificity of 88.0% and 98.7%, respectively. This study established intensity-specific cut-points for wrist-based wear of the Actical accelerometer which are recommended for quantification of moderate and vigorous intensity ambulatory activity.
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