Diagnosis of Leptomeningeal Metastasis in Women With Breast Cancer Through Identification of Tumor Cells in Cerebrospinal Fluid Using the CNSide™ Assay.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Diagnosis of LM is limited by low sensitivity of cerebrospinal fluid (CSF) cytopathology. Detecting tumor cells in CSF (CSF-TCs) might be more sensitive. We evaluated if CNSide (CNSide), a novel assay for tumor cell detection in CSF, can detect CSF-TCs better than conventional CSF cytology.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Clin Breast Cancer

Title: Clinical breast cancer

Publisher: Elsevier BV

ISSN (Electronic): 1938-0666

ISSN (Print): 1526-8209

Publication date (Electronic): Jun 2022

Volume: 22

Issue: 4

Affiliations

[1 ] Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY. Electronic address: maw9199@nyp.org.

[2 ] Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY.

[3 ] Department of Medicine, Yale School of Medicine, New Haven, CT.

[4 ] Biocept Inc., San Diego, CA.

[5 ] Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY.

[6 ] Department of Biostatistics, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY.

[7 ] Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY.

[8 ] Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY; Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY.

[9 ] Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA.

Article

Mid ID: NIHMS1764674 Publisher Item ID: S1526-8209(21)00318-9

DOI: 10.1016/j.clbc.2021.11.002

PMC ID: 9106761

PubMed ID: 34920954

SO-VID: faaff021-a991-4b8b-bf96-8ec0d105531b

History

Data availability:

Comments

Comment on this article

scite_

Cited by 5

See all cited by