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      Identifying areas of Australia with high out-of-hospital cardiac arrest incidence and low bystander cardiopulmonary resuscitation rates: A retrospective, observational study

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          Abstract

          Aim

          This study aims to explore regional variation and identify regions within Australia with high incidence of out-of-hospital cardiac arrest (OHCA) and low rates of bystander cardiopulmonary resuscitation (CPR).

          Method

          Adult OHCAs of presumed medical aetiology occurring across Australia between 2017 and 2019 were mapped onto local government areas (LGA) using the location of arrest coordinates. Bayesian spatial models were applied to provide “smoothed” estimates of OHCA incidence and bystander CPR rates (for bystander-witnessed OHCAs) for each LGA. For each state and territory, high-risk LGAs were defined as those with an incidence rate greater than the state or territory’s 75 th percentile and a bystander CPR rate less than the state or territory’s 25 th percentile.

          Results

          A total of 62,579 OHCA cases attended by emergency medical services across 543 LGAs nationwide were included in the study. Nationally, the OHCA incidence rate across LGA ranged from 58.5 to 198.3 persons per 100,000, while bystander CPR rates ranged from 45% to 75%. We identified 60 high-risk LGAs, which were predominantly located in the state of New South Wales. Within each region, high-risk LGAs were typically located in regional and remote areas of the country, except for four metropolitan areas–two in Adelaide and two in Perth.

          Conclusions

          We have identified high-risk LGAs, characterised by high incidence and low bystander CPR rates, which are predominantly in regional and remote areas of Australia. Strategies for reducing OHCA and improving bystander response may be best targeted at these regions.

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          Most cited references35

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          Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein Resuscitation Registry Templates for Out-of-Hospital Cardiac Arrest: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia); and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation.

          Utstein-style guidelines contribute to improved public health internationally by providing a structured framework with which to compare emergency medical services systems. Advances in resuscitation science, new insights into important predictors of outcome from out-of-hospital cardiac arrest, and lessons learned from methodological research prompted this review and update of the 2004 Utstein guidelines. Representatives of the International Liaison Committee on Resuscitation developed an updated Utstein reporting framework iteratively by meeting face to face, by teleconference, and by Web survey during 2012 through 2014. Herein are recommendations for reporting out-of-hospital cardiac arrest. Data elements were grouped by system factors, dispatch/recognition, patient variables, resuscitation/postresuscitation processes, and outcomes. Elements were classified as core or supplemental using a modified Delphi process primarily based on respondents' assessment of the evidence-based importance of capturing those elements, tempered by the challenges to collect them. New or modified elements reflected consensus on the need to account for emergency medical services system factors, increasing availability of automated external defibrillators, data collection processes, epidemiology trends, increasing use of dispatcher-assisted cardiopulmonary resuscitation, emerging field treatments, postresuscitation care, prognostication tools, and trends in organ recovery. A standard reporting template is recommended to promote standardized reporting. This template facilitates reporting of the bystander-witnessed, shockable rhythm as a measure of emergency medical services system efficacy and all emergency medical services system-treated arrests as a measure of system effectiveness. Several additional important subgroups are identified that enable an estimate of the specific contribution of rhythm and bystander actions that are key determinants of outcome.
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            The global survival rate among adult out-of-hospital cardiac arrest patients who received cardiopulmonary resuscitation: a systematic review and meta-analysis

            Background To quantitatively summarize the available epidemiological evidence on the survival rate of out-of-hospital cardiac arrest (OHCA) patients who received cardiopulmonary resuscitation (CPR). Methods We systematically searched the PubMed, Embase, and Web of Science databases, and the references of retrieved articles were manually reviewed to identify studies reporting the outcome of OHCA patients who received CPR. The overall incidence and outcome of OHCA were assessed using a random-effects meta-analysis. Results A total of 141 eligible studies were included in this meta-analysis. The pooled incidence of return of spontaneous circulation (ROSC) was 29.7% (95% CI 27.6–31.7%), the rate of survival to hospital admission was 22.0% (95% CI 20.7–23.4%), the rate of survival to hospital discharge was 8.8% (95% CI 8.2–9.4%), the pooled 1-month survival rate was 10.7% (95% CI 9.1–13.3%), and the 1-year survival rate was 7.7% (95% CI 5.8–9.5%). Subgroup analysis showed that survival to hospital discharge was more likely among OHCA patients whose cardiac arrest was witnessed by a bystander or emergency medical services (EMS) (10.5%; 95% CI 9.2–11.7%), who received bystander CPR (11.3%, 95% CI 9.3–13.2%), and who were living in Europe and North America (Europe 11.7%; 95% CI 10.5–13.0%; North America: 7.7%; 95% CI 6.9–8.6%). The survival to discharge (8.6% in 1976–1999 vs. 9.9% in 2010–2019), 1-month survival (8.0% in 2000–2009 vs. 13.3% in 2010–2019), and 1-year survival (8.0% in 2000–2009 vs. 13.3% in 2010–2019) rates of OHCA patients who underwent CPR significantly increased throughout the study period. The Egger’s test did not indicate evidence of publication bias for the outcomes of OHCA patients who underwent CPR. Conclusions The global survival rate of OHCA patients who received CPR has increased in the past 40 years. A higher survival rate post-OHCA is more likely among patients who receive bystander CPR and who live in Western countries. Electronic supplementary material The online version of this article (10.1186/s13054-020-2773-2) contains supplementary material, which is available to authorized users.
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              Out-of-hospital cardiac arrest across the World: First report from the International Liaison Committee on Resuscitation (ILCOR)

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                Author and article information

                Contributors
                Role: Formal analysisRole: MethodologyRole: ValidationRole: Writing – original draftRole: Writing – review & editing
                Role: Formal analysisRole: MethodologyRole: Project administrationRole: ValidationRole: Writing – original draftRole: Writing – review & editing
                Role: MethodologyRole: ValidationRole: Writing – review & editing
                Role: ConceptualizationRole: Funding acquisitionRole: MethodologyRole: ValidationRole: Writing – review & editing
                Role: Funding acquisitionRole: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: Funding acquisitionRole: ValidationRole: Writing – review & editing
                Role: ValidationRole: Writing – review & editing
                Role: ConceptualizationRole: Funding acquisitionRole: MethodologyRole: ValidationRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS One
                plos
                PLOS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                23 April 2024
                2024
                : 19
                : 4
                : e0301176
                Affiliations
                [1 ] Queensland Ambulance Service, Brisbane, Queensland, Australia
                [2 ] School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia
                [3 ] Prehospital, Resuscitation and Emergency Care Research Unit (PRECRU), Curtin University, Bentley, Western Australia, Australia
                [4 ] St John Western Australia, Belmont, Western Australia, Australia
                [5 ] Emergency and Trauma Centre, The Alfred, Melbourne, Victoria, Australia
                [6 ] School of Clinical Sciences, Queensland University of Technology, Brisbane City, Queensland, Australia
                [7 ] Hato Hone St John New Zealand, Auckland, New Zealand
                [8 ] Auckland University of Technology, Auckland, New Zealand
                [9 ] NSW Ambulance, Sydney, New South Wales, Australia
                [10 ] Ambulance Victoria, Doncaster, Victoria, Australia
                [11 ] Wellington Free Ambulance, Wellington, New Zealand
                [12 ] SA Ambulance Service, Adelaide, South Australia, Australia
                [13 ] St John Ambulance NT, Darwin, Northern Territory, Australia
                [14 ] ACT Ambulance, Canberra, Australian Capital Territory, Australia
                [15 ] Ambulance Tasmania, Tasmania, Australia
                [16 ] Research and Innovation, Silverchain, Victoria, Australia
                Niigata University of Health and Welfare: Niigata Iryo Fukushi Daigaku, JAPAN
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                https://orcid.org/0000-0002-8158-3273
                https://orcid.org/0000-0002-1443-557X
                https://orcid.org/0000-0002-8151-7356
                https://orcid.org/0000-0002-4189-9433
                https://orcid.org/0000-0002-3316-9043
                Article
                PONE-D-23-19812
                10.1371/journal.pone.0301176
                11037527
                38652707
                f7fe0d50-357f-4a26-a132-b73603926205
                © 2024 Doan et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 12 July 2023
                : 12 March 2024
                Page count
                Figures: 15, Tables: 0, Pages: 19
                Funding
                Funded by: funder-id http://dx.doi.org/10.13039/501100001030, National Heart Foundation of Australia;
                Award ID: 103010
                Funded by: National Health & Medical Research Council
                Award ID: 116453
                Award Recipient :
                Funded by: funder-id http://dx.doi.org/10.13039/501100001030, National Heart Foundation of Australia;
                Award ID: 103010
                Award Recipient :
                Funded by: funder-id http://dx.doi.org/10.13039/501100001030, National Heart Foundation of Australia;
                Award ID: 104751
                Award Recipient :
                Funded by: funder-id http://dx.doi.org/10.13039/501100001030, National Heart Foundation of Australia;
                Award ID: 105690
                Award Recipient :
                Funded by: National Health & Medical Research Council
                Award ID: 1174838
                Award Recipient :
                Funded by: funder-id http://dx.doi.org/10.13039/501100003921, Department of Health and Aged Care, Australian Government;
                Award ID: 1139686
                Award Recipient :
                This study was funded by a National Heart Foundation of Australia grant (#103010) ( https://www.heartfoundation.org.au). SH was funded by the National Health and Medical Research Council (NHMRC: https://www.nhmrc.gov.au) Prehospital Emergency Care Centre of Research Excellence (#116453) and a Heart Foundation of Australia Vanguard Grant (#103010). JB (#104751) and ZN (#105690) were funded by Heart Foundation of Australia Fellowships. JF was supported by NHMRC Investigator Grant (#1174838) and PC by a Medical Research Future Fund Fellowship (#1139686). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                People and Places
                Geographical Locations
                Oceania
                Australia
                Medicine and Health Sciences
                Epidemiology
                Medicine and Health Sciences
                Critical Care and Emergency Medicine
                Resuscitation
                Social Sciences
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                Earth Sciences
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                Medicine and Health Sciences
                Cardiology
                Cardiac Arrest
                Earth Sciences
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                Social Sciences
                Human Geography
                Urban Geography
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                Earth Sciences
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                Custom metadata
                Data are available from the Monash University Human Research Ethics Committee ( MUHREC@ 123456monash.edu ) for researchers who meet the criteria for access to confidential data. These data were sourced from a third party as the data are supplied from ongoing registries maintained by the ambulance services contributing to the paper. The registries contain potentially identifiable information and thus data requests and extracts are performed with regard to the needs of individual projects to maintain confidentiality.

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