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      Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial.

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          Abstract

          Interim results from the children with HIV early antiretroviral (CHER) trial showed that early antiretroviral therapy (ART) was life-saving for infants infected with HIV. In view of the few treatment options and the potential toxicity associated with lifelong ART, in the CHER trial we compared early time-limited ART with deferred ART.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          Nov 09 2013
          : 382
          : 9904
          Affiliations
          [1 ] Children's Infectious Diseases Clinical Research Unit, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa. Electronic address: mcot@sun.ac.za.
          Article
          NIHMS542462 S0140-6736(13)61409-9
          10.1016/S0140-6736(13)61409-9
          4104982
          24209829
          f55411a3-577e-4d44-97c7-c162c5052c75
          Copyright © 2013 Elsevier Ltd. All rights reserved.
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