Minimally and Non-invasive Approaches to Rejection Identification in Vascularized Composite Allotransplantation.

Stead, Thor S; Brydges, Hilliard T.; Laspro, Matteo; Onuh, Ogechukwu C; Chaya, Bachar F.; Rabbani, Piul S.; Lu, Catherine P.; Ceradini, Daniel J; Gelb, Bruce E; Rodriguez, Eduardo D

doi:10.1016/j.trre.2023.100790

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Minimally and Non-invasive Approaches to Rejection Identification in Vascularized Composite Allotransplantation.

Author(s): Thor S Stead ¹ , Hilliard T Brydges ² , Matteo Laspro ² , Ogechukwu C Onuh ² , Bachar F Chaya ² , Piul S Rabbani ² , Catherine P Lu ² , Daniel J Ceradini ² , Bruce E Gelb ³ , Eduardo D Rodriguez ²

Publication date (Electronic): Dec 2023

Journal: Transplantation reviews (Orlando, Fla.)

Publisher: Elsevier BV

Keywords: Acute rejection, Allotransplant, Basic science, Biomarker, Chronic rejection, Diagnosis, Face, Face transplant, Hand, Minimally invasive, Noninvasive, Prognosis, Rejection monitoring, Systematic review, Translational science, Transplant rejection, Vascularized composite allotransplantation

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Abstract

Rejection is common and pernicious following Vascularized Composite Allotransplantation (VCA). Current monitoring and diagnostic modalities include the clinical exam which is subjective and biopsy with dermatohistopathologic Banff grading, which is subjective and invasive. We reviewed literature exploring non- and minimally invasive modalities for diagnosing and monitoring rejection (NIMMs) in VCA.

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Journal ID (iso-abbrev): Transplant Rev (Orlando)

Title: Transplantation reviews (Orlando, Fla.)

Publisher: Elsevier BV

ISSN (Electronic): 1557-9816

ISSN (Print): 0955-470X

Publication date (Electronic): Dec 2023

Volume: 37

Issue: 4

Affiliations

[1 ] Hansjorg Wyss Department of Plastic Surgery, New York University Langone Health, New York, NY, United States of America. Electronic address: thor_stead@brown.edu.

[2 ] Hansjorg Wyss Department of Plastic Surgery, New York University Langone Health, New York, NY, United States of America.

[3 ] Department of Surgery, NYU Grossman School of Medicine, New York, NY, United States of America.

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Publisher Item ID: S0955-470X(23)00044-7

DOI: 10.1016/j.trre.2023.100790

PubMed ID: 37625211

SO-VID: f527a685-0b65-416a-a2c6-8802644cf723

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Keywords: Vascularized composite allotransplantation,Transplant rejection,Translational science,Systematic review,Rejection monitoring,Prognosis,Noninvasive,Minimally invasive,Hand,Face transplant,Face,Diagnosis,Chronic rejection,Biomarker,Basic science,Allotransplant,Acute rejection

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Keywords: Vascularized composite allotransplantation, Transplant rejection, Translational science, Systematic review, Rejection monitoring, Prognosis, Noninvasive, Minimally invasive, Hand, Face transplant, Face, Diagnosis, Chronic rejection, Biomarker, Basic science, Allotransplant, Acute rejection

Minimally and Non-invasive Approaches to Rejection Identification in Vascularized Composite Allotransplantation.

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