Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
28
March
2016
Publication date Collection: 2016
Volume: 11
Issue: 3
Electronic Location Identifier: e0152314
Affiliations
[1
]Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, German Research
Center for Environmental Health, Neuherberg, Germany
[2
]Institute of Epidemiology II, Helmholtz Zentrum Muenchen, German Research Center for
Environmental Health, Neuherberg, Germany
[3
]German Center for Diabetes Research (DZD), Muenchen-Neuherberg, Germany
[4
]Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes
Research at Heinrich Heine University Duesseldorf, Duesseldorf, Germany
[5
]Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center
for Diabetes Research at Heinrich Heine University Duesseldorf, Duesseldorf, Germany
[6
]Institute of Human Genetics, Helmholtz Zentrum Muenchen, German Research Center for
Environmental Health, Neuherberg, Germany
[7
]Institute of Human Genetics, Technische Universitaet Muenchen, Munich, Germany
[8
]Hannover Unified Biobank, Hannover Medical School, Hanover, Germany
[9
]Institute of Human Genetics, Hannover Medical School, Hanover, Germany
[10
]Department of Endocrinology and Diabetology, University Hospital Duesseldorf, Duesseldorf,
Germany
CEA - Institut de Genomique, FRANCE
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Conceived and designed the experiments: JK CH WR CG AP TI HP MR HG. Performed the
experiments: JK SK. Analyzed the data: JK SW SM NV KS MCK. Contributed reagents/materials/analysis
tools: CH WR MW CG AP HP HG. Wrote the paper: JK CH WR SW SK SM NV KS MCK MW CG AP
TI HP MR HG.
‡ These authors also contributed equally to this work.
Article
Publisher ID:
PONE-D-15-44480
DOI: 10.1371/journal.pone.0152314
PMC ID: 4809492
PubMed ID: 27019061
SO-VID: f301d0c9-d641-488a-aad2-7a35786042bf
Copyright © © 2016 Kriebel et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
The KORA study was initiated and financed by the Helmholtz Zentrum München – German
Research Center for Environmental Health, which is funded by the German Federal Ministry
of Education and Research (BMBF) and by the State of Bavaria. Furthermore, KORA research
was supported within the Munich Center of Health Sciences (MC-Health), Ludwig-Maximilians-Universität,
as part of LMUinnovativ. This work was supported by the Ministry of Science and Research
of the State of North Rhine-Westphalia (MIWF NRW) and the German Federal Ministry
of Health (BMG). The diabetes part of the KORA F4 study was funded by a grant from
the German Research Foundation (DFG; RA 459/3-1). This study was supported by the
German Center for Diabetes Research (DZD e.V.).
Subject:
Research Article
Subject:
Biology and life sciences
Subject:
Cell biology
Subject:
Chromosome biology
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Diabetic Endocrinology
Subject:
Insulin
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Hormones
Subject:
Insulin
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Endocrine Disorders
Subject:
Diabetes Mellitus
Subject:
Medicine and Health Sciences
Subject:
Metabolic Disorders
Subject:
Diabetes Mellitus
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Metabolism
Subject:
Carbohydrate Metabolism
Subject:
Glucose Metabolism
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Cell Signaling
Subject:
Glucose Signaling
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Endocrine Physiology
Subject:
Insulin Signaling
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Endocrine Physiology
Subject:
Insulin Signaling
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Endocrine Physiology
Subject:
Insulin Signaling
