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      TLS in Tumors: What Lies Within.

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      Journal: Trends in Immunology

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          Abstract

          The role of tertiary lymphoid structures (TLS) in cancer has recently been illustrated and revisited using mouse models. Joshi et al. describe regulatory T (Treg) cell infiltration and functional heterogeneity of TLS in lung tumors. Finkin et al. report that inflammation-associated TLS serve as niche for tumor progenitor cells, which may lead to recurrence in hepatocellular-carcinoma.

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          PubMed ID:: 26706045
          DOI:: 10.1016/j.it.2015.12.001

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