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      A Schwannoma of the Soft Palate in a Child: Histological and Immunohistochemical Features and Surgical Method

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          Abstract

          Introduction:

          Schwannoma, or neurilemmoma, is a benign neoplasm of Schwann cells that is extremely rare in the soft palate. Herein we present a case of a soft palate schwannoma presenting with an ulcerated surface and purplish colour in a 12 year-old girl. This report also introduces a successful surgical technique for coverage of the defect left by surgery.

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          Most cited references15

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          Neural tumors of the oral cavity. A review of the spectrum of benign and malignant oral tumors of the oral cavity and jaws.

          The clinical and histologic features of benign and malignant neural tumors of the oral cavity and jaws are reviewed. Some rarer histologic variants are mentioned. Particular attention is paid to the two syndromes involving neural tumors of the oral cavity, namely, neurofibromatosis and multiple endocrine neoplasia III. A previously unreported case of the latter is presented.
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            Intra-oral schwannoma: case report and literature review.

            Schwannoma is a relatively uncommon, slow-growing benign tumor that is derived apparently from the Schwann cells. The tongue is the most common site, followed by the palate, floor of mouth, buccal mucosa, lips, and jaws. It can present itself at any age. Usually, this lesion is not taken into account during clinical practice and the differential diagnosis includes numerous benign neoformations based on epithelial and connective tissues. Immunohistochemical features can be useful in determining the neural differentiation. Anti-S100 protein is probably the most used antibody to identify this lesion. The schwannoma is usually a solitary lesion, and can be multiple when associated with neurofibromatosis. In the current study, authors report a case of an intraoral schwannoma situated at the vestibule with 20 years of evolution treated by complete surgical excision. The diagnosis was established based on clinical, histopathological, and immunohistochemical aspects. The patient is under clinical control, with no signs of recurrence even after four years.
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              Myomucosal cheek flaps: applications in intraoral reconstruction using three different techniques.

              The use of myomucosal flaps harvested from the cheek area for intraoral reconstruction has been recently popularized in the literature. Several surgical techniques have been reported, and each study has described the outcomes and advantages of each method. However, the literature lacks a summary of the various surgical techniques utilizing buccinator myomucosal flaps. This paper examines the use of the 3 most important buccinator myomucosal flaps: the buccinator musculomucosal flap, the facial artery musculomucosal flap, and the buccinator musculomucosal island flap. We clarify the applications of each technique in intraoral reconstruction and discuss the indications for, and advantages and disadvantages of, each flap. Forty-six patients who underwent surgical resection for malignancies of the oral cavity and reconstructions with cheek flaps were retrospectively studied. All flaps were harvested and transposed. Complete loss of the flap occurred in only 1 case. In 2 cases, marginal necrosis of the flap took place, with complete spontaneous healing in 2 weeks. Buccinator musculomucosal flaps are a good option for reconstruction of moderately sized oral cavity defects. A key point in this procedure is flap selection based on not only the size and site of the defect, but also the patient's characteristics and type of surgical procedure.
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                Author and article information

                Journal
                Iran J Otorhinolaryngol
                Iran J Otorhinolaryngol
                IJO
                Iranian Journal of Otorhinolaryngology
                Mashhad University of Medical Sciences (Mashhad, Iran )
                2251-7251
                2251-726X
                Spring 2012
                : 24
                : 67
                : 95-99
                Affiliations
                [1 ] Department of oral and maxillofacial surgery, Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
                [2 ] Department of pathology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran .
                [3 ] Department of oral and maxillofacial pathology, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran .
                [4 ] Department of Oral and Maxillofacial Diseases, Oral and Maxillofacial Disease Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
                Author notes
                [* ]Correspondence to:Dental Research Center of Mashhad University of Medical Sciences Vakilabad Blvd, Mashhad, Iran, P.O. Box: 91735-984 , Tel: +98-511-8829501, Fax: +98-511-8829500 , E-mail: khajehahmadis@mums.ac.ir
                Article
                IJO-24-95
                3846209
                24303393
                f02f7778-9f65-465f-b825-a93655e33b5c
                © 2012: Iranian Journal of Otorhinolaryngology

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License, ( http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 27 June 2011
                : 27 December 2011
                Categories
                Case Report

                immunohistochemistry,schwannoma,soft palate,surgical procedures

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