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      Residential Racial Segregation in Aortic Stenosis Diagnosis and Transcatheter Aortic Valve Implantation Among Medicare Patients

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          Abstract

          Background

          Transcatheter aortic valve implantation (TAVI) rates are lower among Black compared with White individuals. However, it is unclear whether racial residential segregation, which remains common in the United States, contributes to observed disparities in TAVI rates.

          Objectives

          The purpose of this study was to evaluate the association between county-level racial segregation, and aortic stenosis (AS) diagnosis, management, and outcomes.

          Methods

          We identified Black and White Medicare fee-for-service beneficiaries age ≥65 years living in metropolitan areas of the United States (2016-2019). Using the American Community Survey’s Black-White residential segregation index, a measure of geographic racial distribution, we determined segregation in each beneficiary’s county of residence. Using hierarchical modeling, we determined the association between racial segregation and rates of AS diagnosis, TAVI receipt, and 30-day clinical outcomes (mortality, readmission, stroke).

          Results

          There were 29,264,075 beneficiaries, of whom 22% lived in a high-segregation county. Among Black beneficiaries, high-segregation county residence was associated with decreased rates of AS diagnosis (OR: 0.97; 95% CI: 0.96-0.98) and TAVI (OR: 0.89; 95% CI: 0.86-0.93) compared with low-segregation county residence. In contrast, among White beneficiaries, high-segregation county residence was associated with higher rates of AS diagnosis (OR: 1.02; 95% CI: 1.02-1.03) and no differences in TAVI (OR: 1.00; 95% CI: 0.99-1.00). Segregation and race were not independently associated with 30-day mortality.

          Conclusions

          Among Black Medicare fee-for-service beneficiaries, living in a high-segregation county was independently associated with decreased rates of AS diagnosis and TAVI, an association not seen among White beneficiaries. Residential racial segregation may contribute to racial disparities seen in AS care.

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          Most cited references36

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          Structural racism and health inequities in the USA: evidence and interventions

          The Lancet, 389(10077), 1453-1463
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            The social determinants of health: coming of age.

            In the United States, awareness is increasing that medical care alone cannot adequately improve health overall or reduce health disparities without also addressing where and how people live. A critical mass of relevant knowledge has accumulated, documenting associations, exploring pathways and biological mechanisms, and providing a previously unavailable scientific foundation for appreciating the role of social factors in health. We review current knowledge about health effects of social (including economic) factors, knowledge gaps, and research priorities, focusing on upstream social determinants-including economic resources, education, and racial discrimination-that fundamentally shape the downstream determinants, such as behaviors, targeted by most interventions. Research priorities include measuring social factors better, monitoring social factors and health relative to policies, examining health effects of social factors across lifetimes and generations, incrementally elucidating pathways through knowledge linkage, testing multidimensional interventions, and addressing political will as a key barrier to translating knowledge into action.
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              Racial residential segregation: A fundamental cause of racial disparities in health

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                Author and article information

                Contributors
                @rwyeh
                Journal
                JACC Adv
                JACC Adv
                JACC: Advances
                Elsevier
                2772-963X
                19 July 2023
                July 2023
                19 July 2023
                : 2
                : 5
                : 100415
                Affiliations
                [a ]Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
                [b ]Harvard Medical School, Boston, Massachusetts, USA
                [c ]Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA
                [d ]Boston Deep Data, Boston, Massachusetts, USA
                [e ]Inova Heart and Vascular Institute, Falls Church, Virginia, USA
                [f ]Division of Cardiology, Duke University, Durham, North Carolina, USA
                [g ]Heart and Vascular Center at Ochsner Lafayette General Hospital, Lafayette, Louisiana, USA
                Author notes
                [] Address for correspondence: Dr Robert W. Yeh, Richard A and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, 375 Longwood Avenue, 4th Floor, Boston, Massachusetts 02215, USA. ryeh@ 123456bidmc.harvard.edu @rwyeh
                Article
                S2772-963X(23)00257-0 100415
                10.1016/j.jacadv.2023.100415
                11198501
                38939010
                eed888bd-24e2-4c6a-a8c5-2b071c7abd85
                © 2023 The Authors

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 6 January 2023
                : 10 April 2023
                : 9 May 2023
                Categories
                Original Research
                Valvular Heart Disease

                aortic stenosis,racial disparities,surgical aortic valve replacement,transcatheter aortic valve implantation

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