Antibodies to MOG and AQP4 in adults with neuromyelitis optica and suspected limited forms of the disease.

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Abstract

We aimed to report the frequency and implications of antibodies to myelin oligodendrocyte glycoprotein (MOG-ab) in adults with demyelinating syndromes suspicious for neuromyelitis optica (NMO).

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Journal

Journal ID (iso-abbrev): Mult. Scler.

Title: Multiple sclerosis (Houndmills, Basingstoke, England)

ISSN (Electronic): 1477-0970

ISSN (Print): 1352-4585

Publication date (Electronic): Jun 2015

Volume: 21

Issue: 7

Affiliations

[1 ] Center of Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain/Institute of Neurology, Medical University of Vienna, Austria/These authors contributed equally to this work.

[2 ] Center of Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain/These authors contributed equally to this work.

[3 ] Center of Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

[4 ] Center of Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain/Department of Pediatrics I, Division of Pediatric Neurology, Innsbruck Medical University, Innsbruck, Austria/Pediatric Neurology, Witten/Herdecke University, Children's Hospital Datteln, Germany.

[5 ] Servicio de Neurología, Hospital Universitari de Bellvitge, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.

[6 ] Hospital Universitario Donostia, San Sebastián, Spain.

[7 ] Hospital Universitari Dr. Josep Trueta, IDIBGI, Girona, Spain.

[8 ] Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.

[9 ] Departament of Neurology, University Hospital "12 de Octubre", Centro de Investigación Biomédica en red sobre Enfermedades Neurodegenerativas (CIBERNED), Departamento de Medicina, Complutense University, Madrid, Spain.

[10 ] Hospital Universitari La Fe de Valencia, Valencia, Spain.

[11 ] Servei de Neurologia-Neuroimunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Vall d'Hebron Institut de Recerca, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

[12 ] Center of Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain/Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

[13 ] Service of Neurology, Hospital Clínic. Villarroel 170, 08036 Barcelona, Spain asaiz@clinic.ub.es.

Article

Publisher Item ID: 1352458514555785 Mid ID: NIHMS768526

DOI: 10.1177/1352458514555785

PubMed ID: 25344373

SO-VID: ec8bf95f-900a-477a-9914-1d72b49a8586

History

Keywords: Neuromyelitis optica,antibodies to myelin oligodendrocyte glycoprotein,aquaporin-4 antibody,longitudinally extensive myelitis,optic neuritis

Data availability:

Keywords: Neuromyelitis optica, antibodies to myelin oligodendrocyte glycoprotein, aquaporin-4 antibody, longitudinally extensive myelitis, optic neuritis

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