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Carotid Ultrasound Identifies High Risk Subclinical Atherosclerosis in Adults with Low Framingham Risk Scores
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Abstract
Worldwide, cardiovascular (CV) disease remains the most common cause of morbidity
and mortality. Although effective in predicting CV risk in select populations, the
Framingham risk score (FRS) fails to identify many young individuals who experience
premature CV events. Accordingly, the aim of this study was to determine the prevalence
of high-risk carotid intima-media thickness (CIMT) or plaque, a marker of atherosclerosis
and predictor of CV events, in young asymptomatic individuals with low and intermediate
FRS (<2% annualized event rate) using the carotid ultrasound protocol recommended
by the American Society of Echocardiography and the Society of Vascular Medicine.